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 ACTICHROME® Heparin (anti-FXa

), activity assay(肝素抗Xa活性发色底物法试剂盒)
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  • ¥6042
  • ACTICHROME
  • 0 - 0.8 U/mL
  • 美国
  • 832
  • 2026年01月04日
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    • 详细信息
    • 询价记录
    • 文献和实验
    • 技术资料
    • 库存

      大量

    • 供应商

      American Diagnostica Inc

    • 检测范围

      0 - 0.8 U/mL

    • 检测方法

      发色底物法

    • 应用

      枸橼酸钠抗凝血浆

    • 样本

      25 μL

    • 规格

      100 tests

    ACTICHROME® Heparin (anti-FXa), activity assay
    肝素抗Xa活性发色底物法试剂盒


    INTENDED USE
    ACTICHROME® Heparin (anti-FXa) is a chromogenic assay intended for the quantitative determination of unfractionated and low molecular weight heparins in human plasma by measurement of factor Xa inhibition.

    PRINCIPLE
    The inhibitory effect of antithrombin III (AT-III) on thrombin, factor Xa and other coagulation serine proteases in plasma is increased several thousandfold by heparin. This inhibition accounts for the anticoagulant effect of heparin. The quantitative determination of plasma heparin levels by the
    measurement of their anti-Xa activity is a necessary tool for monitoring treatment efficacy.

    Low molecular weight heparin (LMWH) preparations appear to catalyze the reaction between factor Xa and AT-III more readily than the reaction between thrombin (FIIa) and AT-III. Unfractionated heparin (UFH) catalyzes both reactions equally. The factor Xa inhibition test is the most useful assay
    covering the widest variety of heparin preparations. In the assay, the rate of factor Xa inhibition is directly proportional to the heparin concentration since both factor Xa and AT-III are in excess. The residual factor Xa activity is inversely proportional to the heparin concentration.1,2

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     ACTICHROME® Heparin (anti-FXa), activity assay(肝素抗Xa活性发色底物法试剂盒)
    ¥6042