- ￥2900
- origene
- TP313277
- 2025年07月07日
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- 详细信息
- 技术资料
- 供应商：
上海研卉生物科技有限公司
- 库存：
20ug
- 英文名：
Estrogen Receptor 1 (ESR1) (NM_000125) Human Recombinant Protein
- 保质期：
一年
- 保存条件：
低温
- 规格：
20ug
Estrogen Receptor 1 (ESR1) (NM_000125) Human Recombinant Protein
| Product Data | |
| Description | Recombinant protein of human estrogen receptor 1 (ESR1), transcript variant 1 |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence | Recombinant protein was produced with TrueORF clone, RC213277. Click on the TrueORF clone link to view cDNA and protein sequences. |
| Tag | C-Myc/DDK |
| Predicted MW | 66 kDa |
| Concentration | >50 ug/mL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
| Bioactivity | Binding assay (PMID: 28842010) |
| Reference Data | |
| Locus ID | 2099 |
| Refseq Size | 6456 |
| Cytogenetics | 6q25.1-q25.2 |
| Refseq ORF | 1785 |
| Synonyms | ER; Era; ESR; ESRA; ESTRR; NR3A1 |
| Summary | This gene encodes an estrogen receptor and ligand-activated transcription factor. The canonical protein contains an N-terminal ligand-independent transactivation domain, a central DNA binding domain, a hinge domain, and a C-terminal ligand-dependent transactivation domain. The protein localizes to the nucleus where it may form either a homodimer or a heterodimer with estrogen receptor 2. The protein encoded by this gene regulates the transcription of many estrogen-inducible genes that play a role in growth, metabolism, sexual development, gestation, and other reproductive functions and is expressed in many non-reproductive tissues. The receptor encoded by this gene plays a key role in breast cancer, endometrial cancer, and osteoporosis. This gene is reported to have dozens of transcript variants due to the use of alternate promoters and alternative splicing, however, the full-length nature of many of these variants remain uncertain. [provided by RefSeq, Jul 2020] |
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Estrogen Receptor 1 (ESR1) (NM_000125) Human Recombinant Protein
￥2900
