- ¥1380 - 2200
- LMAI Bio
- LM-9777R
- 进口/国产
- 2025年11月25日
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200 （石蜡切片需做抗原修复）
- Rabbit
- Human, Mouse, Rat, Rabbit,
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
上海联迈生物工程有限公司
- 库存：
大量
- 目录编号：
LM-9777R
- 克隆性：
多克隆
- 抗原来源：
Rabbit
- 保质期：
1年
- 抗体英文名：
C1orf125
- 抗体名：
1号染色体开放阅读框125抗体
- 宿主：
Rabbit
- 适应物种：
Human, Mouse, Rat, Rabbit,
- 免疫原：
KLH conjugated synthetic peptide derived from human C1orf125:351-450/1021
- 亚型：
IgG
- 形态：
Lyophilized or Liquid
- 应用范围：
WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200 （石蜡切片需做抗原修复）
- 浓度：
1mg/ml
- 保存条件：
Store at -20 °C
- 规格：
100ul 200ul
| 英文名称 | C1orf125 |
| 中文名称 | 1号染色体开放阅读框125抗体 |
| 别 名 | axonemal dynein light chain domain containing 1; AXDN1_HUMAN; AXDND1; Axonemal dynein light chain domain-containing protein 1; DKFZp686H1423; hypothetical protein LOC126859; RP11-215I23.2. |
| 规格价格 | 100ul/1380元 购买 200ul/2200元 购买 大包装/询价 |
| 说 明 书 | 100ul 200ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Rabbit, |
| 产品应用 | WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 118kDa |
| 细胞定位 | 细胞核 细胞浆 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human C1orf125:351-450/1021 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf125 gene product has been provisionally designated C1orf125 pending further characterization. SWISS: Q5T1B0 Gene ID: 126859 Database links:
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品图片 |  Sample: HepG2 Cell (Human) Lysate at 30 ug Primary: Anti- C1orf125 (bs-9777R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 118kD Observed band size: 118kD  Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (C1orf125) Polyclonal Antibody, Unconjugated (bs-9777R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining. |
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文献和实验长度为1450bp即483个密码子，最长的是位于XII号染色体上的一个功能未知的开放阅读框(4910个密码子)，还有极少数的开放阅读框长度超过1500个密码子。在酵母基因组中，也有编码短蛋白的基因，例如，编码由40个氨基酸组成的细胞质 膜蛋白 脂质的PMP1基因。此外，酵母基因组中还包含：约140个编码RNA的基因，排列在XII号染色体的长末端；40个编码SnRNA的基因，散布于16条染色体；属于43个家族的275个tRNA基因也广泛分布于基因组中。 表1 酵母染色体
(ssDNA)分子，4680个核苷酸，在每个末端含有一个145个碱基末端重复序列(TR)（Srivastava等,1983）。TR序列折叠成发卡结构作为DNA复制起始和包装重组AAV基因组为感染性的病毒颗粒所需的唯一已知顺式作用元件。TR元件位于两个翻译开放阅读框(ORF)的两侧。左侧ORF(或rep基因)编码四个非结构蛋白质称为Rep78、68、52和40，对于病毒DNA复制和包装是关键性的。右侧的ORF(或cap基因)编码三个结构蛋白质VP1、VP2和VP3(Berns,1990;Muzyczka
，即整个基因组有72％的核苷酸顺序由开放阅读框组成。这说明酿酒酵母基因要比其它高等真核生物基因排列紧密。如在人类基因组中，大约平均每隔30kb或更多的碱基才能发现一个编码蛋白质的基因。酵母基因组的紧密性是因为基因间隔区较短与基因中内含子稀少。酵母基因组的开放阅读框平均长度为483个密码子，最长的是位于XII号染色体上的一个功能未知的开放阅读框(4910个密码子)。此外，酿酒酵母基因组中还包含有大约140个编码rRNA的基因，排列在XII号染色体的长末端；40个编码snRNA（small nuclear
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