Cardiodilatin-related peptide心舒血管素相关肽抗体

Cardiodilatin-related peptide心

舒血管素相关肽抗体
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  • ¥1380 - 2200
  • LMAI Bio
  • LM-5225R
  • 进口/国产
  • 2025年12月18日
  • WB=1:500-2000 ELISA=1:500-1000 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)
  • Rabbit
  • Human, Mouse, Rat, Dog,
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    • 详细信息
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 目录编号

      LM-5225R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      Cardiodilatin-related peptide

    • 抗体名

      心舒血管素相关肽抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat, Dog,

    • 免疫原

      KLH conjugated synthetic peptide derived from human Cardiodilatin-related peptide:21-100/153

    • 亚型

      IgG

    • 形态

      Lyophilized or Liquid

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)

    • 浓度

      1mg/ml

    • 保存条件

      Store at -20 °C

    • 规格

      100ul  200ul

    Cardiodilatin-related peptide心舒血管素相关肽抗体
    英文名称 Cardiodilatin-related peptide
    中文名称 心舒血管素相关肽抗体
    别    名 Prepronatriodilatin; ANF_HUMAN; ANF; Atrial natriuretic factor; Cardiodilatin related peptide; CDD ANF; CDP; PND; Prepronatriodilatin; Nppa; Natriuretic peptides A; Atrial natriuretic peptide; CDD-ANF; Cardiodilatin-related peptide; ANP.  
    规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 100ul  200ul
    研究领域  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Dog, 
    产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 3/17kDa
    细胞定位 分泌型蛋白 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human Cardiodilatin-related peptide:21-100/153 
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. [provided by RefSeq, Sep 2009].

    Function:
    Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.

    Subunit:
    Interacts with NPR1.

    Subcellular Location:
    Secreted.

    Post-translational modifications:
    Cleaved by CORIN upon secretion to produce the functional hormone.

    DISEASE:
    Atrial fibrillation, familial, 6 (ATFB6) [MIM:612201]: A familial form of atrial fibrillation, a common sustained cardiac rhythm disturbance. Atrial fibrillation is characterized by disorganized atrial electrical activity and ineffective atrial contraction promoting blood stasis in the atria and reduces ventricular filling. It can result in palpitations, syncope, thromboembolic stroke, and congestive heart failure. Note=The disease is caused by mutations affecting the gene represented in this entry.

    Similarity:
    Belongs to the natriuretic peptide family.

    SWISS:
    P01160

    Gene ID:
    4878

    Database links:

    Entrez Gene: 4878 Human

    Entrez Gene: 608289 Dog

    Entrez Gene: 230899 Mouse

    Omim: 108780 Human

    SwissProt: P07499 Dog

    SwissProt: P01160 Human

    SwissProt: P05125 Mouse

    Unigene: 75640 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
     
    产品图片 Cardiodilatin-related peptide心
    Sample:
    Heart (Mouse) Lysate at 40 ug
    Primary: Anti- Cardiodilatin-related peptide (bs-5225R)at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 3/17 kD
    Observed band size: 17 kD

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