NAP2中性粒细胞活性蛋白2/血小板碱性蛋白抗体

NAP2中性粒细胞活性蛋白2/血小板碱性蛋白抗体

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  • ¥780 - 2200
  • LMAI Bio
  • LM-2550R
  • 进口/国产
  • 2025年12月08日
  • WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)
  • Rabbit
  • Human, Mouse, Rat, Pig,
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    • 详细信息
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 目录编号

      LM-2550R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      NAP2

    • 抗体名

      中性粒细胞活性蛋白2/血小板碱性蛋白抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat, Pig,

    • 免疫原

      KLH conjugated synthetic peptide derived from mouse CXCL7:61-130/130

    • 亚型

      IgG

    • 形态

      Lyophilized or Liquid

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)

    • 浓度

      1mg/ml

    • 保存条件

      Store at -20 °C

    • 规格

      50ul  100ul  200ul

    NAP2中性粒细胞活性蛋白2/血小板碱性蛋白抗体
    英文名称 NAP2
    中文名称 中性粒细胞活性蛋白2/血小板碱性蛋白抗体
    别    名 B TG1; Beta TG; b-TG1; beta-TG; NAP-2; NAP2; NAP 2; Beta thromboglobulin; Chemokine (C X C motif) ligand 7; Connective tissue activating peptide III; CTAP 3; CTAP III; CTAP3; CTAPIII; CXC chemokine ligand 7; CXCL 7; CXCL7; LA PF 4; LA-PF4; LDGF; Leukocyte derived growth factor; Low affinity platelet factor IV; MDGF; NAP 2; NAP-2; NAP 2 L1; Neutrophil activating peptide 2; PBP; Platelet basic protein; Platelet basic protein precursor; PPBP; Pro platelet basic protein; SCYB7; Small inducible cytokine B7; Small inducible cytokine subfamily B member 7; TC1; TC2; TGB; TGB1; THBGB; THBGB1; Thrombocidin 1; Thrombocidin 2; Thromboglobulin beta 1.  
    规格价格 50ul/780元 购买    100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 50ul  100ul  200ul
    研究领域 心血管  细胞生物  免疫学  信号转导  生长因子和激素  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Pig, 
    产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 14kDa
    细胞定位 分泌型蛋白 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from mouse CXCL7:61-130/130 
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. [provided by RefSeq, May 2010].

    Function:
    LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation.

    Subunit:
    Beta-thromboglobulin is a homotetramer.

    Subcellular Location:
    Secreted.

    Post-translational modifications:
    Proteolytic removal of residues 1-9 produces the active peptide connective tissue-activating peptide III (CTAP-III) (low-affinity platelet factor IV (LA-PF4)). 
    Proteolytic removal of residues 1-13 produces the active peptide beta-thromboglobulin, which is released from platelets along with platelet factor 4 and platelet-derived growth factor. 
    NAP-2(1-66) is produced by proteolytical processing, probably after secretion by leukocytes other than neutrophils. 
    NAP-2(73) and NAP-2(74) seem not be produced by proteolytical processing of secreted precursors but are released in an active form from platelets.

    Similarity:
    Belongs to the intercrine alpha (chemokine CxC) family.

    SWISS:
    N/A

    Gene ID:
    57349

    Database links:

    Entrez Gene: 5473 Human

    Omim: 121010 Human

    SwissProt: P02775 Human

    Unigene: 2164 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
     
    产品图片 NAP2中性粒细胞活性蛋白2/血小板碱性蛋白抗体
    Tissue/cell: human lung carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; 
    Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; 
    Incubation: Anti-NAP2 Polyclonal Antibody, Unconjugated(bs-2550R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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