PTPRN2胰岛细胞自身抗原相关蛋白PTPRN2抗体

PTPRN2胰岛细胞自身抗原相关蛋白PTPRN2抗体

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  • ¥1380 - 2200
  • LMAI Bio
  • LM-20830R
  • 进口/国产
  • 2025年07月13日
  • WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
  • Rabbit
  • Mouse, Rat,
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    • 详细信息
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 目录编号

      LM-20830R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      PTPRN2

    • 抗体名

      胰岛细胞自身抗原相关蛋白PTPRN2抗体

    • 宿主

      Rabbit

    • 适应物种

      Mouse, Rat,

    • 免疫原

      KLH conjugated synthetic peptide derived from mouse PTPRN2:521-620/1015 <Extracellular>

    • 亚型

      IgG

    • 形态

      Lyophilized or Liquid

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)

    • 浓度

      1mg/ml

    • 保存条件

      Store at -20 °C

    • 规格

      100ul  200ul

    PTPRN2胰岛细胞自身抗原相关蛋白PTPRN2抗体
    英文名称 PTPRN2
    中文名称 胰岛细胞自身抗原相关蛋白PTPRN2抗体
    别    名 IA 2beta; IA2beta; IAR; IAR/receptor like protein tyrosine phosphatase; ICAAR; Islet cell autoantigen related protein; Islet cell autoantigen-related protein; Phogrin; Protein tyrosine phosphatase receptor pi; Protein tyrosine phosphatase, receptor type, N polypeptide 2; PTPR2_HUMAN; Ptprn2; PTPRP; R PTP N2; R-PTP-N2; Receptor-type tyrosine-protein phosphatase N2; Tyrosine phosphatase IA 2 beta.  
    规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 100ul  200ul
    研究领域 细胞生物  信号转导  激酶和磷酸酶  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Mouse, Rat, 
    产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 109kDa
    细胞定位 细胞膜 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from mouse PTPRN2:521-620/1015 <Extracellular>
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]

    Function:
    Implicated in development of nervous system and pancreatic endocrine cells.

    Subcellular Location:
    Membrane.

    Tissue Specificity:
    Highest levels in brain and pancreas. Lower levels in trachea, prostate, stomach and spinal chord.

    Post-translational modifications:
    Appears to undergo multiple proteolytic cleavage at consecutive basic residues. Similarity : Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily. Contains 1 tyrosine-protein phosphatase domain.

    SWISS:
    P80560

    Gene ID:
    19276

    Database links:

    Entrez Gene: 5799 Human

    Entrez Gene: 19276 Mouse

    Entrez Gene: 29714 Rat

    Omim: 601698 Human

    SwissProt: Q92932 Human

    SwissProt: P80560 Mouse

    SwissProt: Q63475 Rat

    Unigene: 490789 Human

    Unigene: 206054 Mouse

    Unigene: 11044 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
     
    产品图片 PTPRN2胰岛细胞自身抗原相关蛋白PTPRN2抗体
    Sample: Heart (Mouse)Lysate at 40 ug
    Primary: Anti-PTPRN2(bs-20830R)at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
    Predicted band size: 109kD
    Observed band size: 109kD

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