PSMG1蛋白酶体组装分子伴侣1抗体

PSMG1蛋白酶体组装分子伴侣1抗体

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  • ¥1380 - 2200
  • LMAI Bio
  • LM-19577R
  • 进口/国产
  • 2025年11月07日
  • WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
  • Rabbit
  • Human, Mouse,
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    • 详细信息
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 目录编号

      LM-19577R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      PSMG1

    • 抗体名

      蛋白酶体组装分子伴侣1抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse,

    • 免疫原

      KLH conjugated synthetic peptide derived from human PSMG1:21-100/288

    • 亚型

      IgG

    • 形态

      Lyophilized or Liquid

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)

    • 浓度

      1mg/ml

    • 保存条件

      Store at -20 °C

    • 规格

      100ul  200ul

    PSMG1蛋白酶体组装分子伴侣1抗体
    英文名称 PSMG1
    中文名称 蛋白酶体组装分子伴侣1抗体
    别    名 AW552102; c21 LRP; PSMG1_HUMAN; C21LRP; Chromosome 21 leucine rich protein; Down syndrome critical region gene 2; Down syndrome critical region protein 2; Down syndrome critical region protein 2 homolog; DSCR2; leucine rich protein C21 LRP; LRPC21; PAC-1; PAC1; proteasome (prosome, macropain) assembly chaperone 1; proteasome assembling chaperone 1; Proteasome assembly chaperone 1.  
    规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 100ul  200ul
    研究领域 细胞生物  信号转导  泛素  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, 
    产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 33kDa
    细胞定位 细胞浆 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human PSMG1:21-100/288 
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    PSMG1 is a chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization. There are two named isoforms.

    Function:
    Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization.

    Subunit:
    Forms a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer interacts directly with the PSMA5 and PSMA7 proteasome alpha subunits.

    Subcellular Location:
    Cytoplasm. Endoplasmic reticulum.

    Tissue Specificity:
    In the adult, detected in brain, colon, leukocytes, breast and testis. Widely expressed in the fetus. Also expressed in a variety of proliferating cell lines.

    Post-translational modifications:
    Degraded by the proteasome upon completion of 20S proteasome maturation.

    Similarity:
    Belongs to the PSMG1 family.

    SWISS:
    O95456

    Gene ID:
    8624

    Database links:

    Entrez Gene: 8624 Human

    Entrez Gene: 56088 Mouse

    Entrez Gene: 288236 Rat

    Omim: 605296 Human

    SwissProt: O95456 Human

    SwissProt: Q9JK23 Mouse



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
     
    产品图片 PSMG1蛋白酶体组装分子伴侣1抗体
    Protein: brain(mouse) lysate at 40ug;
    Primary: rabbit Anti-PSME1 (bs-19575R) at 1:300; 
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 29 kD
    Observed band size: 29 kD

    PSMG1蛋白酶体组装分子伴侣1抗体
    Tissue/cell: human breast carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; 
    Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37∩ for 20 min; 
    Incubation: Anti-PSMG1 Polyclonal Antibody, Unconjugated(bs-19577R) 1:500, overnight at 4∑C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

    PSMG1蛋白酶体组装分子伴侣1抗体
    Tissue/cell: human brain glioma; 4% Paraformaldehyde-fixed and paraffin-embedded; 
    Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37∩ for 20 min; 
    Incubation: Anti-PSMG1 Polyclonal Antibody, Unconjugated(bs-19577R) 1:200, overnight at 4∑C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

    PSMG1蛋白酶体组装分子伴侣1抗体
    Tissue/cell: human cervix carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; 
    Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37∩ for 20 min; 
    Incubation: Anti-PSMG1 Polyclonal Antibody, Unconjugated(bs-19577R) 1:200, overnight at 4∑C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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