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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
上海联迈生物工程有限公司
- 库存:
大量
- 目录编号:
LM-19487R
- 克隆性:
多克隆
- 抗原来源:
Rabbit
- 保质期:
1年
- 抗体英文名:
NT5C1B/RDH14
- 抗体名:
胞浆5'核苷酸酶1B抗体
- 宿主:
Rabbit
- 适应物种:
Human, Mouse, Rat,
- 免疫原:
KLH conjugated synthetic peptide derived from human NT5C1B:1-100/610
- 亚型:
IgG
- 形态:
Lyophilized or Liquid
- 应用范围:
ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
- 浓度:
1mg/ml
- 保存条件:
Store at -20 °C
- 规格:
100ul 200ul
| 英文名称 | NT5C1B/RDH14 |
| 中文名称 | 胞浆5'核苷酸酶1B抗体 |
| 别 名 | 5' nucleotidase cytosolic IB; 5' nucleotidase cytosolic IB isoform CRA_b; 5NT1B_HUMAN; AIRP; Autoimmune infertility-related protein; CN IB; cN-IB; cN1B; CNIB; Cytosolic 5' nucleotidase 1B; Cytosolic 5' nucleotidase IB; Cytosolic 5'-nucleotidase 1B; Cytosolic 5'-nucleotidase IB; MGC26640; Nt5c1b 5' nucleotidase cytosolic IB; NT5C1B; Nt5c1b protein; Nucleotidase 5 prime cytosolic IB; Rdh14. |
| 规格价格 | 100ul/1380元 购买 200ul/2200元 购买 大包装/询价 |
| 说 明 书 | 100ul 200ul |
| 研究领域 | 细胞生物 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 69kDa |
| 细胞定位 | 细胞浆 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NT5C1B:1-100/610 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: This locus represents naturally occurring read-through transcription between the neighboring NT5C1B (5'-nucleotidase, cytosolic IB) and RDH14 (retinol dehydrogenase 14) genes on chromosome 2. Alternative splicing results in multiple transcript variants, one of which encodes a fusion protein that shares sequence identity with the products of each individual gene. [provided by RefSeq, Nov 2010] Function: Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides. Helps to regulate adenosine levels. Subcellular Location: Cytoplasm. Tissue Specificity: Highly expressed in testis, placenta and pancreas. Detected at lower levels in heart, kidney, liver and lung. Similarity: Belongs to the 5'-nucleotidase type 3 family. SWISS: Q96P26 Gene ID: 100526794 Database links: Entrez Gene: 100526794 Human Entrez Gene: 93034 Human Entrez Gene: 70881 Mouse Omim: 610526 Human SwissProt: Q96P26 Human SwissProt: Q91YE9 Mouse Unigene: 120319 Human Unigene: 272843 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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文献和实验7iKmwcf6bs9SgOeZtX4nuJqEW/D/P9kDN4d/QZ30//NiwBEdf/iaSqijYeAKWLx+CSjlIDU0GjhrGrdGuVjHoJ/27L1V2Shy31K5dG6dPn5a+WHv06JEq80jKoL50xCLWkdJFCGaCT3RGX79+hc0xG9y4fh0XL17EoYMHJfuTLFmzwNDQCHXq1EHvvn3SpWAHEs2f37iEnDmJr7D5+PwQR9dtgQsKYVD3EhBivFr1rqim9hh2082
0SoyuWjNKRFlNUuWkgaZA/ixqklm1l/vs6zKrdWyls+m9KIAfxdyEH7qTTSO9buLMbM/QIp9V38iSQ5IxN83EoFIkt9INGNeEYGIQEQgInDgIiCC15AJQlqEs5nul4a0aY8uecHee8mHbYhMC9I6U631iTA27ef3PGQTJ44TEa5bK2YQIqcF/aREMeuyj6imCuKBWetVfhDNotNU2TD3S4srLbIYp+yBIc0ik05ma1ba0W2f/9yX7J//5dv20qpN9tX//hX7zg//j
IL-1b 时,细胞浆中活性形式的ICE也仅占很小的比例。从pro-ICE上剪切下来的原结构域可以抑制ICE的进一步剪切,这可能是一种反馈机制。 (2)ICE识别的剪切位点和特异性抑制剂:ICE识别的剪切位点是一个四肽序列,除了在P1位置的Asp外,还要求在P4位置的氨基酸残基具有一个较大的疏水性集团,P2和P3位置上的氨基酸的变异则较大,P1’位置上一般是一个较小的疏水性氨基酸。根据这一研究结果,人们合成了ICE的人工特异性四
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