产品封面图

CDC2L5 antibody

收藏
  • ¥1380 - 2200
  • 康朗生物
  • kl-7897R
  • 中国/美国/德国
  • 2026年01月04日
  • ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500
  • Rabbit
  • Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
avatar
  • 企业认证

    点击 QQ 联系

    • 详细信息
    • 文献和实验
    • 技术资料
    • 供应商

      上海康朗生物科技有限公司

    • 库存

      大量

    • 目录编号

      kl-7897R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      12个月

    • 抗体英文名

      CDC2L5 antibody

    • 抗体名

      细胞分裂周期2样蛋白激酶5抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat, Dog, Pig, Cow, Sheep,

    • 免疫原

      KLH conjugated synthetic peptide derived from human CDC2L5:601-700/1512

    • 亚型

      IgG

    • 形态

      冻干粉或液体

    • 应用范围

      ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      100ul 200ul

    CDC2L5 antibody
    中文名称 细胞分裂周期2样蛋白激酶5抗体
    别    名 CDC2 related protein kinase 5; CDC2-related protein kinase 5; CDC2L; CDK13; CDK13_HUMAN; cell division controller cholinesterase related; cell division cycle 2 like 5 (cholinesterase related cell division controller); cell division cycle 2 like 5; Cell division cycle 2 like protein kinase 5; Cell division cycle 2-like protein kinase 5; Cell division protein kinase 13; CHED; Cholinesterase related cell division controller; Cholinesterase-related cell division controller; cyclin dependent kinase 13; Cyclin-dependent kinase 13; hCDK13.  
    规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 100ul  200ul
    研究领域 细胞生物  信号转导  细胞周期蛋白  激酶和磷酸酶  表观遗传学  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Sheep, 
    产品应用 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 165kDa
    细胞定位 细胞核 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human CDC2L5:601-700/1512 
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1, thereby acting as a key regulator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis. In case of infection by HIV-1 virus, interacts with HIV-1 Tat protein acetylated at 'Lys-50' and 'Lys-51', thereby increasing HIV-1 mRNA splicing and promoting the production of the doubly spliced HIV-1 protein Nef.
    Tissue specificity:Expressed in fetal brain, liver, muscle and in adult brain. Also expressed in neuroblastoma and glioblastoma tumors.

    Function:
    Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1, thereby acting as a key regulator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis. In case of infection by HIV-1 virus, interacts with HIV-1 Tat protein acetylated at 'Lys-50' and 'Lys-51', thereby increasing HIV-1 mRNA splicing and promoting the production of the doubly spliced HIV-1 protein Nef.

    Subunit:
    Interacts with CCNL1 and CCNL2 (By similarity). Interacts with C1QBP. Interacts with HIV-1 Tat. 

    Subcellular Location:
    Nucleus speckle.

    Tissue Specificity:
    Expressed in fetal brain, liver, muscle and in adult brain. Also expressed in neuroblastoma and glioblastoma tumors. 

    Post-translational modifications:
    Phosphorylated upon DNA damage, probably by ATM or ATR. 

    Similarity:
    Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. 
    Contains 1 protein kinase domain. 

    SWISS:
    Q14004

    Gene ID:
    8621

    Database links:
    UniProtKB/Swiss-Prot: Q14004.2

    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

    风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标文献和实验
    相关实验
    • Generation of Antibody Molecules Through Antibody Engineering

      been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional

    • The Antibody Molecule

      The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera

    • Antibody Storage

        General comments: Antibodies, like most proteins, do not like to be freeze-thawed. Avoid repetitive freezing of your solution. The best way to store your antibody is to keep a high protein concentration (>1 mg/ml), add some protease

    图标技术资料

    暂无技术资料 索取技术资料

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    ¥1700
    GeneTex
    2025年05月18日询价
    ¥1700
    深圳欣博盛生物科技有限公司
    2025年07月14日询价
    ¥2400
    深圳市豪地华拓生物科技有限公司
    2025年07月09日询价
    ¥2000
    上海钰博生物科技有限公司
    2025年05月04日询价
    ¥500
    北京百奥创新科技有限公司
    2025年10月31日询价
    CDC2L5 antibody
    ¥1380 - 2200