SIRT4 antibody

SIRT4 antibody

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  • ¥1380 - 2200
  • 康朗生物
  • kl-7537R
  • 中国/美国/德国
  • 2025年12月12日
  • WB=1:500-2000 ELISA=1:500-1000
  • Rabbit
  • Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Fruit Fly, Zebrafish
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    • 详细信息
    • 技术资料
    • 供应商

      上海康朗生物科技有限公司

    • 库存

      大量

    • 目录编号

      kl-7537R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      12个月

    • 抗体英文名

      SIRT4 antibody

    • 抗体名

      沉默调节相关蛋白4抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Fruit Fly, Zebrafish

    • 免疫原

      KLH conjugated synthetic peptide derived from human SIRT4/SIR 2 like protein 4:51-150/314

    • 亚型

      IgG

    • 形态

      冻干粉或液体

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      100ul 200ul

    SIRT4 antibody
    中文名称 沉默调节相关蛋白4抗体
    别    名 NAD dependent deacetylase sirtuin 4; NAD-dependent ADP-ribosyltransferase sirtuin-4; Silent mating type information regulation 2 homolog; Sir 2 like 4; SIR 2 like protein 4; Sir2 like 4; SIR2 like protein 4; SIR2-like protein 4; SIR2L 4; SIR2L4; SIRT 4; Sirt4; SIRT4_HUMAN; Sirtuin (silent mating type information regulation 2 homolog) 4; Sirtuin (silent mating type information regulation 2 homolog) 4 (S. cerevisiae); Sirtuin 4; Sirtuin type 4; Sirtuin4.  
    SIRT4 antibody Specific References  (2)     |     bs-7537R has been referenced in 2 publications.
    [IF=1.11] Takumida, Masaya, Hiroshi Takumida, and Matti Anniko. "Localization of sirtuins in the mouse inner ear." Acta Oto-Laryngologica 0 (2014): 1-8.  IHC-F ;  Mouse.  
    PubMed:24460154
    [IF=1.10] Takumida, Masaya, et al. "Localization of sirtuins (SIRT1-7) in the aged mouse inner ear." Acta oto-laryngologica (2015): 1-12.  other ;  
    PubMed:26472659
    规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 100ul  200ul
    研究领域 心血管  细胞生物  信号转导  糖尿病  表观遗传学  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Fruit Fly, Zebrafish
    产品应用 WB=1:500-2000 ELISA=1:500-1000 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 32kDa
    细胞定位 细胞浆 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human SIRT4/SIR 2 like protein 4:51-150/314 
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    NAD-dependent protein ADP-ribosyl transferase. Catalyzes the transfer of ADP-ribosyl groups onto target proteins, including mitochondrial GLUD1. Inhibits GLUD1 enzyme activity. Down-regulates insulin secretion. Has no detectable protein deacetylase activity.

    Function:
    NAD-dependent protein ADP-ribosyl transferase. Catalyzes the transfer of ADP-ribosyl groups onto target proteins, including mitochondrial GLUD1. Inhibits GLUD1 enzyme activity. Down-regulates insulin secretion. Has no detectable protein deacetylase activity. 

    Subunit:
    Interacts with GLUD1, IDE and SLC25A5. 

    Subcellular Location:
    Mitochondrion matrix.

    Tissue Specificity:
    Detected in vascular smooth muscle and striated muscle. Detected in insulin-producing beta-cells in pancreas islets of Langerhans (at protein level). Widely expressed. Weakly expressed in leukocytes and fetal thymus. 

    Similarity:
    Belongs to the sirtuin family. Class II subfamily. 
    Contains 1 deacetylase sirtuin-type domain.

    SWISS:
    Q9Y6E7

    Gene ID:
    23409

    Database links:

    Entrez Gene: 519328 Cow

    Entrez Gene: 23409 Human

    Entrez Gene: 75387 Mouse

    Entrez Gene: 100125349 Pig

    Entrez Gene: 304539 Rat

    Omim: 604482 Human

    SwissProt: Q1JQC6 Cow

    SwissProt: Q9Y6E7 Human

    SwissProt: Q8R216 Mouse

    Unigene: 50861 Human

    Unigene: 332616 Mouse



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
     
    产品图片 SIRT4 antibody
    Sample: Cerebrum (Mouse) Lysate at 40 ug
    Primary: Anti-SIRT4 (bs-7537R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 32 kD
    Observed band size: 32 kD

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