- ¥1380 - 2200
- 康朗生物
- kl-7537R
- 中国/美国/德国
- 2025年12月12日
- WB=1:500-2000 ELISA=1:500-1000
- Rabbit
- Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Fruit Fly, Zebrafish
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
上海康朗生物科技有限公司
- 库存：
大量
- 目录编号：
kl-7537R
- 克隆性：
多克隆
- 抗原来源：
Rabbit
- 保质期：
12个月
- 抗体英文名：
SIRT4 antibody
- 抗体名：
沉默调节相关蛋白4抗体
- 宿主：
Rabbit
- 适应物种：
Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Fruit Fly, Zebrafish
- 免疫原：
KLH conjugated synthetic peptide derived from human SIRT4/SIR 2 like protein 4:51-150/314
- 亚型：
IgG
- 形态：
冻干粉或液体
- 应用范围：
WB=1:500-2000 ELISA=1:500-1000
- 浓度：
1mg/ml
- 保存条件：
-20 °C
- 规格：
100ul 200ul
| 中文名称 | 沉默调节相关蛋白4抗体 |
| 别 名 | NAD dependent deacetylase sirtuin 4; NAD-dependent ADP-ribosyltransferase sirtuin-4; Silent mating type information regulation 2 homolog; Sir 2 like 4; SIR 2 like protein 4; Sir2 like 4; SIR2 like protein 4; SIR2-like protein 4; SIR2L 4; SIR2L4; SIRT 4; Sirt4; SIRT4_HUMAN; Sirtuin (silent mating type information regulation 2 homolog) 4; Sirtuin (silent mating type information regulation 2 homolog) 4 (S. cerevisiae); Sirtuin 4; Sirtuin type 4; Sirtuin4. |
 |
Specific References (2) | bs-7537R has been referenced in 2 publications. [IF=1.11] Takumida, Masaya, Hiroshi Takumida, and Matti Anniko. "Localization of sirtuins in the mouse inner ear." Acta Oto-Laryngologica 0 (2014): 1-8. IHC-F ; Mouse. PubMed:24460154 [IF=1.10] Takumida, Masaya, et al. "Localization of sirtuins (SIRT1-7) in the aged mouse inner ear." Acta oto-laryngologica (2015): 1-12. other ; PubMed:26472659 |
| 规格价格 | 100ul/1380元 购买 200ul/2200元 购买 大包装/询价 |
| 说 明 书 | 100ul 200ul |
| 研究领域 | 心血管 细胞生物 信号转导 糖尿病 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Fruit Fly, Zebrafish |
| 产品应用 | WB=1:500-2000 ELISA=1:500-1000 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 32kDa |
| 细胞定位 | 细胞浆 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SIRT4/SIR 2 like protein 4:51-150/314 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: NAD-dependent protein ADP-ribosyl transferase. Catalyzes the transfer of ADP-ribosyl groups onto target proteins, including mitochondrial GLUD1. Inhibits GLUD1 enzyme activity. Down-regulates insulin secretion. Has no detectable protein deacetylase activity. Function: NAD-dependent protein ADP-ribosyl transferase. Catalyzes the transfer of ADP-ribosyl groups onto target proteins, including mitochondrial GLUD1. Inhibits GLUD1 enzyme activity. Down-regulates insulin secretion. Has no detectable protein deacetylase activity. Subunit: Interacts with GLUD1, IDE and SLC25A5. Subcellular Location: Mitochondrion matrix. Tissue Specificity: Detected in vascular smooth muscle and striated muscle. Detected in insulin-producing beta-cells in pancreas islets of Langerhans (at protein level). Widely expressed. Weakly expressed in leukocytes and fetal thymus. Similarity: Belongs to the sirtuin family. Class II subfamily. Contains 1 deacetylase sirtuin-type domain. SWISS: Q9Y6E7 Gene ID: 23409 Database links: Entrez Gene: 519328 Cow Entrez Gene: 23409 Human Entrez Gene: 75387 Mouse Entrez Gene: 100125349 Pig Entrez Gene: 304539 Rat Omim: 604482 Human SwissProt: Q1JQC6 Cow SwissProt: Q9Y6E7 Human SwissProt: Q8R216 Mouse Unigene: 50861 Human Unigene: 332616 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品图片 |  Sample: Cerebrum (Mouse) Lysate at 40 ug Primary: Anti-SIRT4 (bs-7537R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 32 kD Observed band size: 32 kD |
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文献和实验Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera
General comments: Antibodies, like most proteins, do not like to be freeze-thawed. Avoid repetitive freezing of your solution. The best way to store your antibody is to keep a high protein concentration (>1 mg/ml), add some protease
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