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Bone Alkaline Phosphatase anti

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  • ¥1380 - 2200
  • 康朗生物
  • kl-6292R
  • 中国/美国/德国
  • 2026年03月02日
  • WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1ug/Test IF=1:100-500
  • Rabbit
  • Human, Mouse, Rat, Cow, Rabbit,
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    • 详细信息
    • 询价记录
    • 文献和实验
    • 技术资料
    • 供应商

      上海康朗生物科技有限公司

    • 库存

      大量

    • 目录编号

      kl-6292R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      12个月

    • 抗体英文名

      Bone Alkaline Phosphatase antibody

    • 抗体名

      骨碱性磷酸酶抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat, Cow, Rabbit,

    • 免疫原

      KLH conjugated synthetic peptide derived from human Bone Alkaline Phosphatase:56-150/524

    • 亚型

      IgG

    • 形态

      冻干粉或液体

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1ug/Test IF=1:100-500

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      100ul 200ul

    Bone Alkaline Phosphatase antibody
    中文名称 骨碱性磷酸酶抗体
    别    名 AKP2; Alkaline phosphatase liver/bone/kidney; Alkaline phosphatase liver/bone/kidney isozyme; Alkaline phosphatase tissue nonspecific isozyme; Alkaline phosphatase, tissue-nonspecific isozyme; ALPL; AP TNAP; AP-TNAP; APTNAP; BALP; BAP; FLJ40094; FLJ93059; Glycerophosphatase; HOPS; Liver/bone/kidney isozyme; Liver/bone/kidney type alkaline phosphatase; MGC161443; MGC167935; PHOA; PPBT_HUMAN; Tissue non specific alkaline phosphatase; Tissue nonspecific ALP; TNAP; TNSALP.  
    规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 100ul  200ul
    研究领域 肿瘤  细胞生物  免疫学  信号转导  干细胞  激酶和磷酸酶  细胞骨架  细胞外基质  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Cow, Rabbit, 
    产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1ug/Test IF=1:100-500 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 55kDa
    细胞定位 细胞膜 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human Bone Alkaline Phosphatase:56-150/524 
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    Defects in ALPL are a cause of hypophosphatasia (HOPS) . HOPS is an inherited metabolic bone disease characterized by defective skeletal mineralization. Four hypophosphatasia forms are distinguished, depending on the age of onset: perinatal, infantile, childhood and adult type. The perinatal form is the most severe and is almost always fatal. Patients with only premature loss of deciduous teeth, but with no bone disease are regarded as having odontohypophosphatasia.

    Function:
    This isozyme may play a role in skeletal mineralization.

    Subunit:
    Homodimer.

    Subcellular Location:
    Cell membrane; Lipid-anchor, GPI-anchor.

    Post-translational modifications:
    Glycosylated.

    DISEASE:
    Defects in ALPL are a cause of hypophosphatasia (HOPS) [MIM:146300]. HOPS is an inherited metabolic bone disease characterized by defective skeletal mineralization. Four hypophosphatasia forms are distinguished, depending on the age of onset: perinatal, infantile, childhood and adult type. The perinatal form is the most severe and is almost always fatal. Patients with only premature loss of deciduous teeth, but with no bone disease are regarded as having odontohypophosphatasia (odonto).
    Defects in ALPL are a cause of hypophosphatasia childhood type (HOPSC) [MIM:241510].
    Defects in ALPL are a cause of hypophosphatasia infantile type (HOPSI) [MIM:241500]. 

    Similarity:
    Belongs to the alkaline phosphatase family.

    SWISS:
    P05186

    Gene ID:
    249

    Database links:

    Entrez Gene: 249 Human

    Entrez Gene: 11647 Mouse

    Entrez Gene: 25586 Rat

    Omim: 171760 Human

    SwissProt: P05186 Human

    SwissProt: P09242 Mouse

    SwissProt: P08289 Rat

    Unigene: 75431 Human

    Unigene: 288186 Mouse

    Unigene: 82764 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
     
    产品图片 产品细节图片1
    Sample: 
    Heart (Mouse) Lysate at 40 ug
    Primary: Anti-Bone Alkaline Phosphatase (bs-6292R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 55 kD
    Observed band size: 55 kD

    产品细节图片2
    Blank control (blue line): Hep G2(fixed with 70% ethanol Overnight at 4℃). 
    Primary Antibody (green line): Rabbit Anti-Bone Alkaline Phosphatase antibody (bs-6292R),Dilution: 1μg /10^6 cells. 
    Isotype Control Antibody (orange line): Rabbit IgG .
    Secondary Antibody (white blue line): Goat anti-rabbit IgG-PE,Dilution: 1μg /test. 

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    • Histochemical staining of sea urchin embryos for alkaline phosphatase (AP) enzyme activity

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    ¥1380 - 2200