ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量
169kDa
细胞定位
细胞膜
性 状
Lyophilized or Liquid
浓 度
1mg/ml
免 疫 原
KLH conjugated synthetic peptide derived from human Brain Specific Angiogenesis Inhibitor 2:701-800/1585 <Extracellular>
亚 型
IgG
纯化方法
affinity purified by Protein A
储 存 液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed
PubMed
产品介绍
background: BAI1, a p53-target gene, encodes brain-specific angiogenesis inhibitor, a seven-span transmembrane protein and is thought to be a member of the secretin receptor family. Brain-specific angiogenesis proteins BAI2 and BAI3 are similar to BAI1 in structure, have similar tissue specificities and may also play a role in angiogenesis.
Function: Might be involved in angiogenesis inhibition.
Subunit: Interacts with GABPB2 (By similarity).
Subcellular Location: Cell Membrane
Tissue Specificity: Strongly expressed in brain. Also detected in heart, thymus, skeletal muscle, and different cell lines.
Similarity: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. Contains 1 GPS domain. Contains 4 TSP type-1 domains.
SWISS: O60241
Gene ID: 576
Database links:
Entrez Gene: 576 Human
Entrez Gene: 230775 Mouse
Entrez Gene: 313058 Rat
Omim: 602683 Human
SwissProt: O60241 Human
SwissProt: Q8CGM1 Mouse
Unigene: 200586 Human
Unigene: 262241 Mouse
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.