重组小鼠IL-27价格

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专注于生命科学和生物技术领域，致力于为客户提供包括重组小鼠IL-27价格在内的一系列分子生物学试剂产品，并提供一系列相关的技术服务。

名称：重组小鼠IL-27价格
编号：JN1645
规格：10μg|50μg|500μg|1mg
英文名：Recombinant Mouse Interleukin-27 subunit alpha and Interleukin-27 subunit beta
品牌：百奥莱博
产地：北京
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Tyr19-Pro228&Phe29-Ser234在C端含有His标签。

IL-27质量控制：＞95%(还原性SDS-PAGE)

IL-27制剂：冻干品

IL-27保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

IL-27复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于IL-27：
IL-27 is a heterodimeric cytokine which belongs to the IL-6/IL-12 family of long type I cytokines. It is expressed on monocytes, endothelial cells and dendritic cells. IL-27 is an early product of activated antigen-presenting cells and drives rapid clonal expansion of naive CD4(+) T cells and plays a role in the early regulation of Th1 cells initiation which drives efficient adaptive immune response. IL-27 potentiates the early phase of TH1 response and suppresses TH2 and TH17 differentiation. It induces the differentiation of TH1 cells via two distinct pathways, p38 MAPK/TBX21- and ICAM1/ITGAL/ERK-dependent pathways. It also induces STAT1, STAT3, STAT4 and STAT5 phosphorylation and activates TBX21/T-Bet via STAT1 with resulting IL12RB2 up-regulation, an event crucial to TH1 cell commitment. IL-27 has an antiproliferative activity on melanomas through WSX-1/STAT1 signaling. Thus, IL-27 protein may be an attractive candidate as an antitumor agent applicable to cancer immunotherapy. IL-27 reveals to be a potent inhibitor of TH17 cell development and of IL-17 production. Indeed IL27 alone is also able to inhibit the production of IL17 by CD4 and CD8 T-cells. IL-27 has also an effect on cytokine production. It suppresses proinflammatory cytokine production such as IL2, IL4, IL5 and IL6 and activates suppressors of cytokine signaling such as SOCS1 and SOCS3. Apart from suppression of cytokine production, IL-27 also antagonizes the effects of some cytokines such as IL6 through direct effects on T-cells. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines such as IP-10/CXCL10 and MIG/CXCL9.

我公司的重组小鼠IL-27价格，性价比高，货期短，送货上门，欢迎您来电咨询购买，另外，我公司还生产供应销*(代"售")下列产品：

·重组人*离子/*调蛋白依赖性蛋白激酶1D(CAMK1D)
编号：JN1077
英文名称：Recombinant Human Calcium/Calmodulin-Dependent Protein Kinase Type ID
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Lys385在N端带有GST标签。

CAMK1D质量控制：＞95%(还原性SDS-PAGE)

CAMK1D制剂：液体

CAMK1D保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于CAMK1D：
CAMK1D is a serine?threonine kinase that is a member of the calcium?calmodulin-dependent protein kinase family. It contains a protein kinase domain. CAMK1D expressed in polymorphonuclear leukocytes and may be part of the chemokine signal transduction pathway that regulates granulocyte function. It may also be involved in modulation of neuronal apoptosis. It activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and promotes basal dendritic growth of hippocamp*(代"a")l neurons.

·重组人前折叠素亚基2(PFDN2)
编号：JN2024
英文名称：Recombinant Human Prefoldin Subunit 2
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Ser154在N端含有His标签。

PFDN2质量控制：＞95%(还原性SDS-PAGE)

PFDN2制剂：冻干品

PFDN2保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

PFDN2复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于PFDN2：
Prefoldin Subunit 2 (PFDN2) belongs to the Prefoldin Beta subunit family. The PFDN2 protein is one of six subunits of Prefoldin that act as a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. PFDN2 binds specifically to Cytosolic Chaperonin (c-CPN) and transfers target proteins to it. PFDN2 also binds to a nascent polypeptide chain and promotes folding in settings where there are many competing pathways for non-native proteins.


重组小鼠IL-27价格关键词：重组小鼠IL-27蛋白,重组IL-27,JN1645,Recombinant Mouse Interleukin-27 subunit alpha and,百奥莱博


·重组人α-2-HS-Glycoprotein
编号：JN0557
英文名称：Recombinant Human alpha-2-HS-Glycoprotein
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ala19-Val367在C端含有His标签。

α-2-HS-Glycoprotein质量控制：＞95%(还原性SDS-PAGE)

α-2-HS-Glycoprotein制剂：冻干品

α-2-HS-Glycoprotein保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

α-2-HS-Glycoprotein复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于α-2-HS-Glycoprotein：
α-2-HS Glycoprotein (AHSG) is a glycoprotein that is composed of two subunits, the A and B chains, belongs to the Cystatin family of proteases inhibitors. It is highly expressed in embryonic cells and adult hepatocytes, and is expressed to a lesser extent in monocytes/macrophages. AHSG is an important circulating inhibitor of calcification in vivo, and is downregulated during the acute-phase response. It is involved in several functions, such as endo*(代"c")ytosis, brain development and the formation of bone tissue. In addition, AHSG may influence the resolution of inflammation by modulating the phagocytosis of apoptotic cells by macrophages. ASHG blocks TGF-beta-dependent signaling in osteoblastic cells.


重组小鼠IL-27价格关键词：重组小鼠IL-27蛋白,重组IL-27,JN1645,Recombinant Mouse Interleukin-27 subunit alpha and,百奥莱博


·重组人GSTP1
编号：JN1387
英文名称：Recombinant Human Glutathione S-Transferase pi 1
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Glu210表达纯化得来。

GSTP1质量控制：＞95%(还原性SDS-PAGE)

GSTP1制剂：液体

GSTP1保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于GSTP1：
Glutathione S-transferase P (GSTP1) is an enzyme that contains 1 GST C-terminal domain, 1 GST N-terminal domain.GSTP1 belongs to the GST superfamily, the GSTs are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta.The glutathione S-transferase pi gene (GSTP1) is a polymorphic gene encoding active, functionally different GSTP1 variant proteins. Besides, it regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration. It thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.

我公司正在火爆促销重组蛋白系列产品，欢迎您的垂询选购重组小鼠IL-27价格。