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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
上海康朗生物科技有限公司
- 库存:
大量
- 目录编号:
kl-17347R
- 克隆性:
多克隆
- 抗原来源:
Rabbit
- 保质期:
12个月
- 抗体英文名:
HNRPUL1 antibody
- 抗体名:
异质核核糖核蛋白U样蛋白1抗体
- 宿主:
Rabbit
- 适应物种:
Human, Mouse, Rat, Cow, Horse, Cat,
- 免疫原:
KLH conjugated synthetic peptide derived from human HNRPUL1:701-800/856
- 亚型:
IgG
- 形态:
冻干粉或液体
- 应用范围:
WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500
- 浓度:
1mg/ml
- 保存条件:
-20 °C
- 规格:
100ul 200ul
中文名称异质核核糖核蛋白U样蛋白1抗体别 名Adenovirus early region 1B associated protein 5; Adenovirus early region 1B-associated protein 5; E130317O14Rik; E1B 55 kDa associated protein 5; E1B AP5; E1B-55 kDa-associated protein 5; E1B-AP5; E1BAP5; fb53d10; fk45c03; FLJ12944; Heterogeneous nuclear ribonucleoprotein U-like protein 1; HNRL1_HUMAN; Hnrnpul1; HNRPUL1; MGC36621; MGC78330; wu:fb53d10; wu:fk45c03; zgc:85971. 规格价格100ul/1380元 购买 200ul/2200元 购买 大包装/询价说 明 书100ul 200ul研究领域细胞生物 转录调节因子 结合蛋白 表观遗传学 抗体来源Rabbit克隆类型Polyclonal交叉反应Human, Mouse, Rat, Cow, Horse, Cat, 产品应用WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.分 子 量96kDa细胞定位细胞核 性 状Lyophilized or Liquid浓 度1mg/ml免 疫 原KLH conjugated synthetic peptide derived from human HNRPUL1:701-800/856 亚 型IgG纯化方法affinity purified by Protein A储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.PubMedPubMed产品介绍background:
This gene encodes a nuclear RNA-binding protein of the heterogeneous nuclear ribonucleoprotein (hnRNP) family. This protein binds specifically to adenovirus E1B-55kDa oncoprotein. It may play an important role in nucleocytoplasmic RNA transport, and its function is modulated by E1B-55kDa in adenovirus-infected cells. Two transcript variants encoding different isoforms have been found for this gene. Additional variants have also been found, but their full-length natures have not been determined. [provided by RefSeq, Jul 2008]
Function:
Acts as a basic transcriptional regulator. Represses basic transcription driven by several virus and cellular promoters. When associated with BRD7, activates transcription of glucocorticoid-responsive promoter in the absence of ligand-stimulation. Plays also a role in mRNA processing and transport. Binds avidly to poly(G) and poly(C) RNA homopolymers in vitro.
Subcellular Location:
Nucleus.
Post-translational modifications:
Methylated.
Similarity:
Contains 1 B30.2/SPRY domain.
Contains 1 SAP domain.
SWISS:
Q9BUJ2
Gene ID:
11100
Database links:
Entrez Gene: 11100 Human
Entrez Gene: 232989 Mouse
Entrez Gene: 361522 Rat
Omim: 605800 Human
SwissProt: Q9BUJ2 Human
SwissProt: Q8VDM6 Mouse
Unigene: 155218 Human
Unigene: 718642 Human
Unigene: 254223 Mouse
Unigene: 95170 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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文献和实验Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera
General comments: Antibodies, like most proteins, do not like to be freeze-thawed. Avoid repetitive freezing of your solution. The best way to store your antibody is to keep a high protein concentration (>1 mg/ml), add some protease
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