- ¥1380 - 2200
- 康朗生物
- kl-15368R
- 中国/美国/德国
- 2025年07月13日
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500
- Rabbit
- Human, Mouse, Rat, Chicken, Cow, Horse,
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
上海康朗生物科技有限公司
- 库存：
大量
- 目录编号：
kl-15368R
- 克隆性：
多克隆
- 抗原来源：
Rabbit
- 保质期：
12个月
- 抗体英文名：
GPCR LGR7 antibody
- 抗体名：
G蛋白偶联受体LGR7蛋白抗体
- 宿主：
Rabbit
- 适应物种：
Human, Mouse, Rat, Chicken, Cow, Horse,
- 免疫原：
KLH conjugated synthetic peptide derived from human GPCR LGR7:301-400/757 <Extracellular>
- 亚型：
IgG
- 形态：
冻干粉或液体
- 应用范围：
WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500
- 浓度：
1mg/ml
- 保存条件：
-20 °C
- 规格：
100ul 200ul
| 中文名称 | G蛋白偶联受体LGR7蛋白抗体 |
| 别 名 | Gm1018; Leucine rich repeat containing G protein coupled receptor 7;LGR7; LGR7.1; LGR7.10; LGR7.2; MGC138347; MGC142177; Relaxin family peptide receptor 1; Relaxin receptor 1; Relaxin/insulin like family peptide receptor 1; RXFP 1; RXFP1; RXFP1; RXFP1_HUMAN; RXFPR1. |
| 规格价格 | 100ul/1380元 购买 200ul/2200元 购买 大包装/询价 |
| 说 明 书 | 100ul 200ul |
| 研究领域 | 细胞生物 免疫学 信号转导 G蛋白偶联受体 G蛋白信号 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Cow, Horse, |
| 产品应用 | WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 87kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GPCR LGR7:301-400/757 <Extracellular> |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane receptor superfamily. The encoded protein plays a critical role in sperm motility, pregnancy and parturition as a receptor for the protein hormone relaxin. Decreased expression of this gene may play a role in endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] Function: Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in the brain, kidney, testis, placenta, uterus, ovary, adrenal, prostate, skin and heart. Not detected in spleen. Similarity: Belongs to the G-protein coupled receptor 1 family. Contains 1 LDL-receptor class A domain. Contains 9 LRR (leucine-rich) repeats. Contains 1 LRRNT domain. SWISS: Q9HBX9 Gene ID: 59350 Database links: Entrez Gene: 59350 Human Entrez Gene: 381489 Mouse Entrez Gene: 295144 Rat Omim: 606654 Human SwissProt: Q9HBX9 Human SwissProt: Q6R6I7 Mouse SwissProt: Q6R6I6 Rat Unigene: 591686 Human Unigene: 331086 Mouse Unigene: 109230 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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文献和实验Flow Cytometry Assay to Measure Internalization of GPCR
Flow Cytometry Assay to Measure Internalization of GPCR's contributed by Patricia Tsao Internalization of receptor is measured as the reduction of receptors on the plasma membrane surface. Surface receptors
Flow Cytometry Assay to Measure Internalization of GPCR's
Flow Cytometry Assay to Measure Internalization of GPCR's contributed by Patricia Tsao Internalization of receptor is measured
Discovery and Characterization of Leucine-Rich Repeat-Containing G Protein-Coupled Receptors
, and LH); a pair of receptors for insulin-like peptides (LGR7, LGR8); and the LGR4, LGR5, and LGR6 receptors, which are the basis of this chapter. LGRs were initially identified as conceptual proteins extracted from DNA sequence databases, displaying
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