BRN4 antibody

BRN4 antibody

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  • ¥1380 - 2200
  • 康朗生物
  • 中国/美国/德国
  • 2025年11月25日
  • ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1μg /Test IF=1:50-200
  • Rabbit
  • Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
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    • 详细信息
    • 技术资料
    • 供应商

      上海康朗生物科技有限公司

    • 库存

      大量

    • 目录编号

      kl-8202R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      12个月

    • 抗体英文名

      BRN4 antibody

    • 抗体名

      脑转录因子4蛋白抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,

    • 免疫原

      KLH conjugated synthetic peptide derived from human BRN4/POU3F4:211-320/361

    • 亚型

      IgG

    • 形态

      冻干粉或液体

    • 应用范围

      ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1μg /Test IF=1:50-200

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      100ul 200ul

    BRN4 antibody
    中文名称 脑转录因子4蛋白抗体
    别    名 class 3; transcription factor 4; Brain specific homeobox POU domain protein 4; Brain-4; Brain-specific homeobox/POU domain protein 4; BRAIN4; Brn-4; BRN4; DFN3; Oct-9; Octamer-binding protein 9; Octamer-binding transcription factor 9; OTF-9; OTF9; PO3F4_HUMAN; POU domain; POU domain class 3 transcription factor 4; POU3F4.  
    规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 100ul  200ul
    研究领域 细胞生物  免疫学  神经生物学  表观遗传学  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
    产品应用 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1μg /Test IF=1:50-200 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 39kDa
    细胞定位 细胞核 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human BRN4/POU3F4:211-320/361 
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    Probable transcription factor which exert its primary action widely during early neural development and in a very limited set of neurons in the mature brain.Defects in POU3F4 are a cause of deafness X-linked type 2 (DFNX2) . A mixed type of deafness characterized by both conductive hearing loss resulting from stapes (perilymphatic gusher) fixation and progressive sensorineural deafness.

    Function:
    Probable transcription factor which exert its primary action widely during early neural development and in a very limited set of neurons in the mature brain. 

    Subcellular Location:
    Nucleus.

    Tissue Specificity:
    Brain specific.

    DISEASE:
    Defects in POU3F4 are a cause of deafness X-linked type 2 (DFNX2) [MIM:304400]. A mixed type of deafness characterized by both conductive hearing loss resulting from stapes (perilymphatic gusher) fixation and progressive sensorineural deafness.

    Similarity:
    Belongs to the POU transcription factor family. Class-3 subfamily. 
    Contains 1 homeobox DNA-binding domain. 
    Contains 1 POU-specific domain. 

    SWISS:
    P49335

    Gene ID:
    5456

    Database links:

    Entrez Gene: 5456 Human

    Entrez Gene: 18994 Mouse

    Entrez Gene: 29589 Rat

    Omim: 300039 Human

    SwissProt: P49335 Human

    SwissProt: P62515 Mouse

    SwissProt: P62516 Rat

    Unigene: 2229 Human

    Unigene: 405149 Mouse

    Unigene: 56946 Mouse

    Unigene: 33030 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
     
    产品图片 BRN4 antibody
    Blank control(blue): RSC96(fixed with 2% paraformaldehyde (10 min) and then permeabilized with ice-cold 90% methanol for 30 min on ice). 
    Primary Antibody:Rabbit Anti-BRN4 antibody(bs-8202R), Dilution: 1μg in 100 μL 1X PBS containing 0.5% BSA; 
    Isotype Control Antibody: Rabbit IgG(orange) ,used under the same conditions ); 
    Secondary Antibody: Goat anti-rabbit IgG-PE(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA.

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