- ¥1159
- 联迈生物
- LM6015-10μg
- 中国/上海
- 2025年07月09日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
大量
- 英文名：
Recombinant Murine M-CSF
- 保质期：
一年
- 供应商：
上海联迈生物工程有限公司
- 保存条件：
-20℃或更低温度保存
- 规格：
10μg
| 产品编号 | 产品名称 | 产品包装 | 产品价格 |
| LM6015-10μg | Recombinant Murine M-CSF | 10μg | 1159.00元 |
| Species | Gene ID | Accession | Source | Length | MW | Tag |
| Mouse | 12977 | LM07141 | E. coli | 230aa | 52kDa | － |
| About this Antibody | |
| Name | Recombinant Murine M-CSF (Recombinant Murine Macrophage Colony Stimulating Factor; rMuM-CSF)；Recombinant Mouse M-CSF ; 重组小鼠巨噬细胞集落刺激因子 |
| Synonyms | CSF1; CSF-1; colony stimulating factor 1 (macrophage); CSF-1; Lanimostim; macrophage colony stimulating factor; macrophage colony-stimulating factor 1; M-CSF; MCSFlanimostim; MGC31930 |
| Purity | >95% by SDS-PAGE and HPLC analyses. |
| Biological Activity | Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine M-NFS-60 cells is less than 2ng/ml, corresponding to a specific activity of >5.0×105IU/mg. |
| Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation | Lyophilized from a 0.2μm filtered solution in 20mM Tris, 500mM NaCl, pH7.4. |
| Endotoxin | Less than 1EU/μg of rMuM-CSF as determined by LAL method. |
| Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions. |
| Category | Cytokine |
| Background | Macrophage Colony Stimulating Factor (M-CSF), also named CSF-1, is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. It is produced by osteoblasts (as a result of endocrine stimulation by parathyroid hormone) exerts paracrine effects on osteoclasts and can interact with CSF1R. M-CSF is a four α-helical bundle cytokine and its active form is found extracellularly as a disulfide-linked homodimer. Four transcript variants encoding three different isoforms have been reported for M-CSF gene. Although forms may vary, all of them contain the N-terminal 150a.a. portion that is necessary and sufficient for interaction with the receptor. The first 229a.a. of mature mouse M-CSF shares 87%, 83%, 82% and 81% sequence identity with corresponding regions of rat, dog, cow and human M-CSF, respectively. Human M-CSF is active in the mouse, but mouse M-CSF is reported to be species-specific. |
| Amino Acid Sequence | KEVSEHCSHM IGNGHLKVLQ QLIDSQMETS CQIAFEFVDQ EQLDDPVCYL KKAFFLVQDI IDETMRFKDN TPNANATERL QELSNNLNSC FTKDYEEQNK ACVRTFHETP LQLLEKIKNF FNETKNLLEK DWNIFTKNCN NSFAKCSSRD VVTKPDCNCL YPKATPSSDP ASASPHQPPA PSMAPLAGLA WDDSQRTEGS SLLPSELPLR IEDPGSAKQR PPRSTCQTLE |
| 产品编号 | 产品名称 | 包装 |
| LM6015-2μg | Recombinant Murine M-CSF | 2μg |
| LM6015-10μg | Recombinant Murine M-CSF | 10μg |
| LM6015-100μg | Recombinant Murine M-CSF | 100μg |
| LM6015-1mg | Recombinant Murine M-CSF | 1mg |
| - | 说明书 | 1份 |
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
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