Recombinant Human IL-17B

Recombinant Human IL-17B

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  • ¥15444
  • 联迈生物
  • LM5205-1mg
  • 中国/上海
  • 2025年07月16日
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    • 详细信息
    • 技术资料
    • 库存

      大量

    • 英文名

      Recombinant Human IL-17B

    • 保质期

      一年

    • 供应商

      上海联迈生物工程有限公司

    • 保存条件

      -20℃或更低温度保存

    • 规格

      1mg

    Recombinant Human IL-17B
    产品编号 产品名称 产品包装 产品价格
    LM5205-1mg Recombinant Human IL-17B 1mg 15444.00
     
    Species Gene ID Accession Source Length MW Tag
    Human 27190 LM9UHF5 E. coli 161aa 36.5kDa
     
    About this protein
    Name Recombinant Human IL-17B (Recombinant Human Interleukin-17B; rHuIL-17B);重组人白细胞介素17B
    Synonyms Cytokine Zcyto7; cytokine-like protein ZCYTO7; IL-17Binterleukin-17 beta; IL20; IL-20interleukin-17B; interleukin 17B; interleukin 20; Interleukin-20; MGC138900; MGC138901; neuronal interleukin-17 related factor; Neuronal interleukin-17-related factor; NIRF; ZCYTO7interleukin-20
    Purity >95% by SDS-PAGE and HPLC analyses.
    Biological Activity Fully biologically active when compared to standard. The ED50 as determined by inducing IL-8 secretion of human HepG2 cells is less than 1.0μg/ml, corresponding to a specific activity of >1000IU/mg.
    Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder.
    Formulation Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4, with 0.1% Tween-20 and 3% Trehalose.
    Endotoxin Less than 0.1EU/μg of rHuIL-17B as determined by LAL method.
    Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.
    Category Cytokine
    Background IL-17B, also named IL20, NIRF and ZCYTO7, is belonging to the IL-17 family and it stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1. IL-17B mRNA is expressed in adult pancreas, small intestine, and stomach. The IL-17 family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17B binds the IL-17B receptor, but not the IL-17 receptor; it is most homologous with IL-17D, which is expressed by resting CD4+ T cells and CD19+ B cells. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies.
    Amino Acid Sequence MQPRSPKSKR KGQGRPGPLA PGPHQVPLDL VSRMKPYARM EEYERNIEEM VAQLRNSSEL AQRKCEVNLQ LWMSNKRSLS PWGYSINHDP SRIPVDLPEA RCLCLGCVNP FTMQEDRSMV SVPVFSQVPV RRRLCPPPPR TGPCRQRAVM ETIAVGCTCI F
    包装清单:
    产品编号 产品名称 包装
    LM5205-5μg Recombinant Human IL-17B 5μg
    LM5205-25μg Recombinant Human IL-17B 25μg
    LM5205-100μg Recombinant Human IL-17B 100μg
    LM5205-1mg Recombinant Human IL-17B 1mg
    - 说明书 1
    保存条件:
           -20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
    注意事项:
           由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
           本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
           为了您的安全和健康,请穿实验服并戴一次性手套操作。


     

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