特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博专业生产销*(代"售")重组人PDCD1(PD-1)(CD279 mutant) 重组蛋白,我公司供应的分子生物学试剂品类齐全,且具有优势价格,欢迎新老客户垂询订购。
名称:重组人PDCD1(PD-1)(CD279 mutant) 重组蛋白
产地:国产|进口
规格:10μg|50μg|500μg|1mg
英文名:Recombinant Human Programmed Cell Death Protein 1 mutant
品牌:百奥莱博
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Leu25-Gln167,Cys93Ser在C端含有His标签。
PDCD1/PD-1/CD279 mutant质量控制:>95%(还原性SDS-PAGE)
PDCD1/PD-1/CD279 mutant制剂:冻干品
PDCD1/PD-1/CD279 mutant保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
PDCD1/PD-1/CD279 mutant复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于PDCD1/PD-1/CD279 mutant:
Programmed cell death protein 1(PDCD1) is a single-pass type I membrane protein and contains 1 Ig-like V-type domain. PD-1 is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN-γ by suppressing the activation and transduction of PI3K/AKT pathway. In addition, coligation of PDCD1 inhibits BCR-mediating signal by dephosphorylating key signal transducer. PDCD1 has been suggested to be involved in lymphocyte clonal selection and peripheral tolerance, and thus contributes to the prevention of autoimmune diseases. As a cell surface molecule, PDCD1 regulates the adaptive immune response. Engagement of PD-1 by its ligands PD-L1 or PD-L2 transduces a signal that inhibits T-cell proliferation, cytokine production, and cytolytic function.
欲了解更多重组人PDCD1(PD-1)(CD279 mutant) 重组蛋白的品牌、产地、价格及说明书等产品信息,请致电北京百奥莱博科技有限公司,我们将竭诚为您服务,另外,以下产品正在火爆促销:
·重组人锌指蛋白75A(ZNF75A)
编号:JN0898
英文名称:Recombinant Human Zinc Finger Protein 75A
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Ser58-Lys162在N端含有His标签。
ZNF75A质量控制:>95%(还原性SDS-PAGE)
ZNF75A制剂:冻干品
ZNF75A保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
ZNF75A复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于ZNF75A:
Zinc Finger Protein 75A (ZNF75A) is a member of krueppel C2H2-type zinc-finger protein family. The human ZNF75 gene is located on Xq26, which has only limited homology (less than 65%) to other ZF genes in the databases. One of these, ZNF75B is a pseudogene mapped to chromosome 12q13. The other two, ZNF75A and ZNF75C, maintain an ORF in the sequenced region, and at least the latter is expressed in the U937 cell line. ZNF75A contains five C2H2-type zinc fingers and one KRAB domain. ZNF75A is a nucleus protein, may involves in transcriptional regulation.
重组人PDCD1(PD-1)(CD279 mutant) 重组蛋白关键词:重组人PDCD1蛋白,JN1527,重组人PD-1,重组人CD279 mutant
·重组人E26转录因子1(转录因子ETS-1)(ETS1)
编号:JN0956
英文名称:Recombinant Human E26 Transformation-Specific 1
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Thr272在N端含有His标签。
ETS1质量控制:>95%(还原性SDS-PAGE)
ETS1制剂:冻干品
ETS1保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
ETS1复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于ETS1:
ETS1 Protein (ETS1) is a nuclear protein that belongs to the ETS family. Members of this family recognize the core consensus DNA sequence GGAA/T in target genes. Proteins function either as transcriptional activators or repressors of numerous genes. They are involved in stem cell development, cell senescence and death, and tumorigenesis. ETS1 is a transcription factor, containing one ETS DNA-binding domain and one PNT (pointed) domain. it has been shown to interact with TTRAP, UBE2I and Death Associated Protein 6.
重组人PDCD1(PD-1)(CD279 mutant) 重组蛋白关键词:重组人PDCD1蛋白,JN1527,重组人PD-1,重组人CD279 mutant
·重组小鼠CCL8(MCP-2)
编号:JN1646
英文名称:Recombinant Mouse C-C motif Chemokine 8
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Glu20-Pro97在C端含有His标签。
CCL8/MCP-2质量控制:>95%(还原性SDS-PAGE)
CCL8/MCP-2制剂:冻干品
CCL8/MCP-2保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
CCL8/MCP-2复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于CCL8/MCP-2:
Chemokine ligand 8 (CCL8,MCP-2), is a small secreted cytokine which belongs to the intercrine beta (chemokine CC) family. CCL8 Chemotactic factor attracts monocytes. It can bind heparin.CCL8 functions to activate different immune cells, including mast cells, eosinophils and basophils which are involved in allergic responses, monocytes, and T cells and NK cells which are involved in the inflammatory response. Its ability achieves by binding to different cell surface receptors termed chemokine receptors including CCR1, CCR2B and CCR5. It has been reported that CCL8 is a potent inhibitor of HIV-1 by virtue of its binding to CCR5 which is one of the major co-receptors for HIV-1.
我公司生产供应销*(代"售")的重组蛋白正全品类优惠促销,十分期待您的咨询选购重组人PDCD1(PD-1)(CD279 mutant) 重组蛋白。