重组人过氧化物还原蛋白1(Peroxiredoxin 1)

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博主要从事生物试剂的生产和销*(代"售")，产品线涵盖重组人过氧化物还原蛋白1(Peroxiredoxin 1) 重组蛋白在内的分子生物学试剂产品，还包括PCR及荧光定量PCR、核酸提取试剂盒类、样本核酸保护试剂、核酸提取、克隆与转化、蛋白纯化、蛋白检测、免疫组化、细胞凋亡与抗体等。

名称：重组人过氧化物还原蛋白1(Peroxiredoxin 1) 重组蛋白
编号：JN1204
产地：国产|进口
英文名：Recombinant Human Peroxiredoxin-1
品牌：百奥莱博
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Lys199在N端、C端都带有His标签。

Peroxiredoxin 1质量控制：＞95%(还原性SDS-PAGE)

Peroxiredoxin 1制剂：液体

Peroxiredoxin 1保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于Peroxiredoxin 1：
Peroxiredoxin-1(PRDX1) contains 1 thioredoxin domain and belongs to the AhpC/TSA family. PRDX1 constitutively expressed in most human cells and it is induced to higher levels upon serum stimulation in untransformed and transformed cells. PRDX1 is involved in redox regulation of the cell. It reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin and play an important role in eliminating peroxides generated during metabolism. PRDX1 might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2. It reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation. It may contribute to the antiviral activity of CD8(+) T-cells and have a proliferative effect in cancer development or progression.

欲了解更多重组人过氧化物还原蛋白1(Peroxiredoxin 1) 重组蛋白的品牌、产地、价格及说明书等产品信息，请致电北京百奥莱博科技有限公司，我们将竭诚为您服务，另外，以下产品正在火爆促销:

·重组人半胱*酸蛋白酶ATG4C(自噬相关蛋白酶ATG4C)
编号：JN1753
英文名称：Recombinant Human Autophagy Related 4 Homolog C
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Leu458在C端含有His标签。

ATG4C质量控制：＞95%(还原性SDS-PAGE)

ATG4C制剂：液体

ATG4C保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于ATG4C：
Cysteine Protease ATG4C (ATG4C) belongs to the peptidase C54 family. It is required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form which is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. ATG4C is a cytoplasmic protein and high expressed in skeletal muscle, liver, testis and heart. ATG4C can be inhibited by N-ethylmaleimide.

·卡那霉素溶液(10mg/ml)
编号：JN0118
英文名称：Recombinant Human Autophagy Related 4 Homolog C
规格：1ml×10
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Leu458在C端含有His标签。

ATG4C质量控制：＞95%(还原性SDS-PAGE)

ATG4C制剂：液体

ATG4C保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于ATG4C：
Cysteine Protease ATG4C (ATG4C) belongs to the peptidase C54 family. It is required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form which is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. ATG4C is a cytoplasmic protein and high expressed in skeletal muscle, liver, testis and heart. ATG4C can be inhibited by N-ethylmaleimide.


重组人过氧化物还原蛋白1(Peroxiredoxin 1) 重组蛋白关键词：重组人过氧化物还原蛋白1,重组过氧化物还原蛋白1,重组人Peroxiredoxin 1,JN1204,重组人过氧化物还原蛋白1蛋白


·重组人上皮细胞粘附分子(EpCAM)(TROP1)
编号：JN1498
英文名称：Recombinant Human Epithelial cell adhesion molecule
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Gln24-Lys265在C端带有Fc标签。

EpCAM/TROP1质量控制：＞95%(还原性SDS-PAGE)

EpCAM/TROP1制剂：冻干品

EpCAM/TROP1保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

EpCAM/TROP1复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于EpCAM/TROP1：
Epithelial Cell Adhesion Molecule (EpCAM) is a signal type I transmembrane glycoprotein that belongs to the EPCAM family. EpCAM is composed of an extracellular domain with one thyroglobulin type-1 domain, a transmembrane domain and a cytoplasmic domain. EpCAM is found on the surface of adenocarcinoma, but not on mesodermal or neural cell membranes. The EpCAM molecule has been shown to function as a homophilic Ca2+ independent adhesion molecule. It may act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium as an immunological barrier providing the first line of defense against infection. Defects in EPCAM are a cause of hereditary non-polyposis colorectal cancer type 8 (HNPCC8) and diarrhea type 5 (DIAR5). EpCAM plays a role in embryonic stem cells proliferation and differentiation; it up-regulates the expression of FABP5, MYC and Cyclin A and Cyclin E. It is highly and selectively expressed by undifferentiated embryonic stem cells.


重组人过氧化物还原蛋白1(Peroxiredoxin 1) 重组蛋白关键词：重组人过氧化物还原蛋白1,重组过氧化物还原蛋白1,重组人Peroxiredoxin 1,JN1204,重组人过氧化物还原蛋白1蛋白


·重组人癌胚抗原相关细胞粘附分子5(CD66E)(CEACAM5)
编号：JN1552
英文名称：Recombinant Human Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Lys35-Ala685在C端带有Fc标签。

CD66E/CEACAM5质量控制：＞95%(还原性SDS-PAGE)

CD66E/CEACAM5制剂：冻干品

CD66E/CEACAM5保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

CD66E/CEACAM5复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于CD66E/CEACAM5：
Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to a group of mammalian immunoglobulin related glycoproteins. They play critical roles in cell–cell recognition. CEACAM5, also called CEA and CD66e, is characterized by having seven extracellular Ig domains and a glycosylphosphatidylinositol (GPI) anchor. CEACAM5 is expressed primarily by epithelial cells, and functions as a calcium-independent adhesion molecule through homophilic and heterophilic interactions with CEACAM1. Studies have shown that CEACAM5 is overexpressed in a majority of carcinomas, and its overexpression can protect tumor cells from apoptosis. It is commonly used as a cancer marker.

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