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- 技术资料
- 库存:
607
- 英文名:
Recombinant Human 5-Nucleotidase
- 保质期:
6个月
- 供应商:
北京百奥莱博科技有限公司
- 保存条件:
收到货后请置于-20℃
特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博专业生产销*(代"售")重组人CD73(5-Nucleotidase)打折促销,我公司供应的分子生物学试剂品类齐全,且具有优势价格,欢迎新老客户垂询订购。
名称:重组人CD73(5-Nucleotidase)打折促销
规格:10μg|50μg|500μg|1mg
英文名:Recombinant Human 5-Nucleotidase
品牌:百奥莱博
产地:国产|进口
编号:JN1833
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Trp27-Lys547在C端含有His标签。
CD73/5-Nucleotidase质量控制:>95%(还原性SDS-PAGE)
CD73/5-Nucleotidase制剂:液体
CD73/5-Nucleotidase保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于CD73/5-Nucleotidase:
CD73 is a glycosyl phosphatidylinositol (GPI) anchored membrane protein that belongs to the 5-nucleotidase family. CD73 is an ecto 5Nucleotidase expressed by most cell types. CD73 hydrolyzes extracellular nucleotides into membrane permeable nucleosides. CD73 is one of several enzymes responsible for the production of extracellular adenosine, a signaling molecule that is involved in responses to inflammation and tissue injury. CD73 is a lymphocyte maturation marker that has functions independent of its catalytic activity. CD73 is also a regulator of leukocyte extravasation, a function that requires its 5Nucleotidase activity. Defects in NT5E are the cause of calcification of joints and arteries (CAJA). The recombinant CD73 lacking GPI anchor is secreted as a monomer.
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重组人CD73(5-Nucleotidase)打折促销关键词:JN1833,重组人5-Nucleotidase,重组人CD73蛋白,重组CD73
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重组人CD73(5-Nucleotidase)打折促销关键词:JN1833,重组人5-Nucleotidase,重组人CD73蛋白,重组CD73
·重组小鼠TGF-beta RII(C端含His标签)
编号:JN1461
英文名称:Recombinant Mouse Transforming Growth Factor-beta Receptor Type II
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Ile24-Asp159在C端含有His标签。
TGF-beta RII质量控制:>95%(还原性SDS-PAGE)
TGF-beta RII制剂:冻干品
TGF-beta RII保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
TGF-beta RII复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于TGF-beta RII:
Transforming growth factor-β (TGF-β) is an essential regulator in the processes of development, cell proliferation, and extracellular matrix deposition. TGF-β regulates cellular processes by binding to three high-affinity cell surface receptors: TGF-β receptor type I (TGF-β-RI), TGF-β receptor type II (TGF-β-RII), and TGF-ββ receptor type III (TGF-β-RIII). TGF-β RII is consists of a C-terminal protein kinase domain and an N-terminal ectodomain and belongs to transforming growth factor-beta (TGF-β) receptor subfamily. TGF-β RII has a protein kinase domain which can form a heterodimeric complex with another receptor protein and bind TGF-beta. This receptor/ligand complex phosphorylates protein will enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation.
北京百莱博科技有限公司专业生产供应销*(代"售")生物试剂、化学试剂、抗原抗体、血清血浆、Elisa试剂盒,更多试剂产品需求,欢迎来电咨询选购重组人CD73(5-Nucleotidase)打折促销。
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文献和实验CD73 分子 CD73 常用单克隆抗体或代号: 7G2.2.11,AD- 2 主要表达细胞: Bsub,Tsub,En [B] 分子质量(kDa)和结构: p69(GPI连接) 功 能: 5’-核苷酸外切酶,T细胞活化 CD73 Aka ecto-5-nucleotidase, PI-linked Catalyses dephosphorylation of purine
Nucleotide Metabolism and Cell-Cell Interactions
adenine nucleotides after activation (adenosine triphosphate [ATP] and adenosine monophosphate [AMP]). ATP and AMP are metabolized by endothelial cell-surface enzymes, the ecto-apyrase (CD39, metabolizes ATP to AMP) and the 5’-ecto-nucleotidase (CD73
Characterization of P1 (Adenosine) Purinoceptors
., Thompson, L.F., Unertl, K., and Eltzschig, H.K. 2007. Cardioprotection by ecto‐5′‐nucleotidase (CD73) and A2B adenosine receptors. Circulation 115:1581‐1590. Emson, P.C. and Koob
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