北京现货重组人泛素羧基末端水解酶14(USP14)优惠

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博主要从事生物试剂的生产和销*(代"售")，产品线涵盖北京现货重组人泛素羧基末端水解酶14(USP14)优惠在内的分子生物学试剂产品，还包括PCR及荧光定量PCR、核酸提取试剂盒类、样本核酸保护试剂、核酸提取、克隆与转化、蛋白纯化、蛋白检测、免疫组化、细胞凋亡与抗体等。

名称：北京现货重组人泛素羧基末端水解酶14(USP14)优惠
品牌：百奥莱博
规格：10μg|50μg|500μg|1mg
编号：JN1971
产地：国产|进口
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Asp91-Gln494在N端含有His标签。

USP14质量控制：＞95%(还原性SDS-PAGE)

USP14制剂：液体

USP14保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于USP14：
Ubiquitin Carboxyl-Terminal Hydrolase 14 (USP14) belongs to the ubiquitin-specific processing (USP) family which is a deubiquitinating enzyme (DUB) with His and Cys domains. USP14 located in the cytoplasm is a proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. USP14 acts also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. In addition, USP14 is indispensable for synaptic development and function at neuromuscular junctions, required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis.

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北京现货重组人泛素羧基末端水解酶14(USP14)优惠关键词：JN1971,重组人USP14,重组人泛素羧基末端水解酶14蛋白,重组泛素羧基末端水解酶14


·重组人IGFBP-5(胰岛素样生长因子结合蛋白5)
编号：JN0817
英文名称：Recombinant Human Insulin-Like Growth Factor-Binding Protein 5
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Leu21-Glu272在C端含有His标签。

IGFBP-5质量控制：＞95%(还原性SDS-PAGE)

IGFBP-5制剂：冻干品

IGFBP-5保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

IGFBP-5复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于IGFBP-5：
Insulin-Like Growth Factor-Binding Protein 5 (IGFBP-5) is a secreted protein that belongs to the insulin-like growth factor (IGF) binding proteins superfamily. Members of this family prolong the half-life of the IGFs. They have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. IGFBP-5 contains one IGFBP N-terminal domain and one thyroglobulin type-1 domain. IGFBP-5 is expressed by fibroblasts, myoblasts and Osteosarcoma. It is also present at lower levels in liver, kidney, and brain.


北京现货重组人泛素羧基末端水解酶14(USP14)优惠关键词：JN1971,重组人USP14,重组人泛素羧基末端水解酶14蛋白,重组泛素羧基末端水解酶14


·重组小鼠Legumain(天冬酰胺肽链内切酶)(天冬*酸内肽酶)
编号：JN1806
英文名称：Recombinant Mouse Legumain/Asparaginyl Endopeptidase
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Val18-Tyr435在C端含有His标签。

Legumain质量控制：＞95%(还原性SDS-PAGE)

Legumain制剂：液体

Legumain保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于Legumain：
Mouse Legumain,also known as LGMN, is a cysteine protease belonging to peptidase family C13 and is expressed in kidney and placenta abundantly. LGMN has a strict specificity for hydrolysis of asparaginyl bonds. It can also cleave aspartyl bonds slowly, especially under acidic conditions. The mammalian legumain is involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system. It plays a role in the regulation of cell proliferation via its role in EGFR degradation. Legumain deficiency causes the accumulation of pro-Cathepsins B, H and L, another group of lysosomal cysteine proteases. Overexpression of Legumain in tumors is significant for invasion/metastasis. Mammalian legumain is inhibited by iodoacetamide and maleimides. Legumain activation appears to be autocatalytic and can be triggered by acidic pH.

我公司正在优惠促销重组蛋白等系列产品，期待您的咨询选购北京现货重组人泛素羧基末端水解酶14(USP14)优惠。