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颗粒细胞瘤基因表达PCR芯片可用于研究直接或可能参与颗粒细胞瘤基因的57个关键基因的表达。该基因表达PCR芯片包括已知的颗粒细胞瘤基因表达相关的基因和它们的调控基因。利用该芯片研究者可以方便并且可信地研究颗粒细胞瘤相关基因的表达。
| Gene ID | Gene Symbol | Gene Description |
| 207 | AKT1 | AKT serine/threonine kinase 1 |
| 268 | AMH | anti-Mullerian hormone |
| 269 | AMHR2 | anti-Mullerian hormone receptor type 2 |
| 367 | AR | androgen receptor |
| 596 | BCL2 | BCL2, apoptosis regulator |
| 598 | BCL2L1 | BCL2 like 1 |
| 6046 | BRD2 | bromodomain containing 2 |
| 894 | CCND2 | cyclin D2 |
| 1499 | CTNNB1 | catenin beta 1 |
| 1555 | CYP2B6 | cytochrome P450 family 2 subfamily B member 6 |
| 1616 | DAXX | death domain associated protein |
| 23405 | DICER1 | dicer 1, ribonuclease III |
| 1956 | EGFR | epidermal growth factor receptor |
| 2064 | ERBB2 | erb-b2 receptor tyrosine kinase 2 |
| 2099 | ESR1 | estrogen receptor 1 |
| 2100 | ESR2 | estrogen receptor 2 |
| 2300 | FOXL1 | forkhead box L1 |
| 668 | FOXL2 | forkhead box L2 |
| 2308 | FOXO1 | forkhead box O1 |
| 2309 | FOXO3 | forkhead box O3 |
| 2492 | FSHR | follicle stimulating hormone receptor |
| 10468 | FST | follistatin |
| 2626 | GATA4 | GATA binding protein 4 |
| 2661 | GDF9 | growth differentiation factor 9 |
| 2798 | GNRHR | gonadotropin releasing hormone receptor |
| 2852 | GPER1 | G protein-coupled estrogen receptor 1 |
| 94031 | HTRA3 | HtrA serine peptidase 3 |
| 3623 | INHA | inhibin alpha subunit |
| 3791 | KDR | kinase insert domain receptor |
| 9622 | KLK4 | kallikrein related peptidase 4 |
| 3845 | KRAS | KRAS proto-oncogene, GTPase |
| 3973 | LHCGR | luteinizing hormone/choriogonadotropin receptor |
| 5595 | MAPK3 | mitogen-activated protein kinase 3 |
| 2475 | MTOR | mechanistic target of rapamycin |
| 4855 | NOTCH4 | notch 4 |
| 190 | NR0B1 | nuclear receptor subfamily 0 group B member 1 |
| 23569 | PADI4 | peptidyl arginine deiminase 4 |
| 5111 | PCNA | proliferating cell nuclear antigen |
| 5241 | PGR | progesterone receptor |
| 5315 | PKM | pyruvate kinase, muscle |
| 80316 | PPP1R2P9 | protein phosphatase 1 regulatory inhibitor subunit 2 pseudogene 9 |
| 5728 | PTEN | phosphatase and tensin homolog |
| 864 | RUNX3 | runt related transcription factor 3 |
| 4086 | SMAD1 | SMAD family member 1 |
| 4088 | SMAD3 | SMAD family member 3 |
| 4090 | SMAD5 | SMAD family member 5 |
| 6597 | SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 |
| 6598 | SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 |
| 6770 | STAR | steroidogenic acute regulatory protein |
| 7039 | TGFA | transforming growth factor alpha |
| 8277 | TKTL1 | transketolase like 1 |
| 8743 | TNFSF10 | tumor necrosis factor superfamily member 10 |
| 7157 | TP53 | tumor protein p53 |
| 7258 | TSPY1 | testis specific protein, Y-linked 1 |
| 7415 | VCP | valosin containing protein |
| 7422 | VEGFA | vascular endothelial growth factor A |
| 54361 | WNT4 | Wnt family member 4 |
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文献和实验简介:什么是PCR芯片? 实时定量PCR是检测基因表达最灵敏,最可靠的方法。通过在试验过程中,实时监测荧光染料的信号变化,反映样品中的基因拷贝数。实时定量PCR线性范围广(能达到5个数量级),因此可以检测同一样品中表达量极低的基因和表达量很高的基因。但是,由于实时定量PCR需要制备标准曲线和同时分析内参基因,因此,每次实验只能检测少数几个基因的表达水平,若要检测大量基因,则工作量巨大,耗时长久。 通过简单的,经过优化的实时定量PCR体系,如SuperArray的RT2ProfilerTM
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Array-CGH Analysis of Cutaneous Anaplastic Large Cell Lymphoma
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