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- prospecbio
- ANT-148
- 以色列
- 2025年07月16日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
大量
- 英文名：
CD8, Mouse Anti-Human
- 保质期：
1年
- 供应商：
上海沪震实业有限公司
- 保存条件：
-20°C
- 规格：
500µg/1mg
CATALOGUE NUMBER
ANT-148
SYNONYMS
CD8, MAL, p32.TYPE
Mouse Anti Human Monoclonal.INTRODUCTION
CD8 is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 acts as a co-receptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional CD8 is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.CD8 identifies cytotoxic/suppressor t-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of t-cell mediated killing. CD8 alpha chains binds to class-I MHC molecules alpha-3 domains.
CLONE
hCD8.IMMUNOGEN
Purified human PBL CD8+ T cells.IG SUBCLASS
Mouse IgG2a.PURIFICATION METHOD
Ion exchange column.FORMULATION
1mg/ml in PBS (after reconstitution).STORAGE PROCEDURES
Lyophilized: store at 4oC. After reconstitution, if not intended for use within a month, aliquot and store at -20oC.SOLUBILITY
Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.APPLICATIONS
Blocking and staining antibody. For staining, use 10µl/1,000,000 cells. Titer for blocking T cell activation should be determined by the investigator.AVAILABLE CONJUGATES
This antibody is also available conjugated to biotin and FITC. For staining with biotin or FITC-conjugated antibody use 5-10µl/106 cells.USAGE
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Purification of Immature CD4+CD8+ Thymocytes by Panning with Anti-CD8 Antibody
Most T lymphocytes of the immune system differentiate within the thymus along the CD4/CD8 developmental pathway by a highly ordered process termed thymic selection ( 1 , 2 ). The maturation status of thymocytes is commonly assessed
CD8 分子 CD8 常用单克隆抗体或代号：α链：T8，Leu2a，UCHT4， β链：T8／2T8，5H7 主要表达细胞：Tsub(α/β，Thysub，IEL，NKsub(α/α)[T] 分子质量(kDa)和结构：gp(36／32)，α/α或α/β二聚体(1sSF) 功 能：与MHCI类分子结合，信号转号 CD8 Aka OKT
CD8+, CD8, and Plasmacytoid Dendritic Cell Generation In Vitro Using flt3 Ligand
in detail for the generation of the phenotypic, functional, and developmental equivalents of CD8+ , CD8− , and plasmacytoid DCs. This includes growth and purification of recombinant flt3 ligand from Chinese hamster ovary cells, isolation of bone marrow cells, and phenotypic
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