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- 详细信息
- 技术资料
- 抗体名:
环指蛋白31抗体
- 抗体英文名:
Anti-RNF31/HOIP
- 靶点:
详见说明书
- 浓度:
1mg/1ml
- 应用范围:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200
- 宿主:
详见说明书
- 供应商:
上海一研
- 库存:
32
- 级别:
详见说明书
- 目录编号:
详见说明书
- 抗原来源:
Rabbit
- 保质期:
详见说明书
- 适应物种:
详见说明书
- 标记物:
详见说明书
- 克隆性:
多克隆
- 保存条件:
Store at -20 °C
- 形态:
详见说明书
- 亚型:
IgG
- 免疫原:
KLH conjugated synthetic peptide derived from human RNF31/HOIP
- 规格:
0.2ml/200μg
公司抗体应用于WB、IHC、IF、ELISA等实验中,环指蛋白31抗体价格品质保证,提供完善的售前、售中、售后服务!欢迎来电咨询或联系在线客服!我们将竭诚为您服务!
英文名称 Anti-RNF31/HOIP
中文名称 环指蛋白31抗体价格
别 名 HOIL 1L interacting protein; HOIL-1-interacting protein; HOIL-1L interacting protein; HOIL1L interacting protein; HOIP; RING finger protein 31; RNF31; RNF31_HUMAN; ZIBRA; Zinc in between ring finger ubiquitin associated domain; Zinc in-between-ring-finger ubiquitin associated domain; Zinc in-between-RING-finger ubiquitin-associated domain protein; FLJ10111; FLJ23501
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Horse, Rabbit
产品类型 一抗
研究领域 细胞生物 染色质和核信号 信号转导 转录调节因子 表观遗传学
蛋白分子量 predicted molecular weight: 118kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human RNF31/HOIP
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 E3 ubiquitin-protein ligase component of the LUBAC complex which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation. LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex. Binds polyubiquitin of different linkage types.
Function : E3 ubiquitin-protein ligase component of the LUBAC complex which conjugates linear ('M-1'-linked) polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation. LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex. Binds polyubiquitin of different linkage types.
Subunit : Interacts with MUSK. Component of the LUBAC complex (linear ubiquitin chain assembly complex) which consists of SHARPIN, RBCK1 and RNF31. LUBAC has a MW of approximative 600 kDa suggesting a heteromultimeric assembly of its subunits. Associates with the TNF-R1 signaling complex (TNF-RSC) in a stimulation-dependent manner. Contains 1 UBA domain.
Subcellular Location : Cytoplasm.
Tissue Specificity : Expressed in both normal and transformed breast epithelial cell lines.
Similarity : Contains 1 IBR-type zinc finger.
Contains 3 RanBP2-type zinc fingers.
Contains 2 RING-type zinc fingers.
Contains 1 UBA domain.
环指蛋白31抗体价格具有高度的特异性,免疫组织化学正是利用了这一原理。先将组织或细胞中的某种化学物质提取出来,以此作为抗原或半抗原,通过免疫动物后获得特异性的抗体,再以此抗体去探测组织或细胞中的同类的抗原物质。由于抗原与抗体的复合物是无色的,因此还必须借助于组织化学的方法将抗原抗体结合的部位显示出来,以其达到对组织或细胞中的未知抗原进行定性,定位或定量的研究。
环指蛋白31抗体价格包括以下几个步骤:
1、制备抗原。
2、选择实验动物。
3、动物免疫。
4、试取血进行测试,看看是否成功免疫。
5、如果成功免疫,杀死实验动物,采集全部血清。
6、纯化出抗体。
7、鉴定抗体。包括纯度以及特异性。
环指蛋白31抗体价格的功能
抗体的主要功能是与抗原(包括外来的和自身的)相结合,从而有效地清除侵入机体内的微生物、寄生虫等异物,抗体(antibody)是一种应答抗原产生的、可与抗原特异性结合的蛋白质。每种抗体与特定的抗原决定基结合。这种结合可以使抗原失活,也可能无效但有时也会对机体造成病理性损害,如抗核抗体、抗双链DNA抗体、抗甲状腺球蛋白抗体等一些自身抗体的产生,对人体可造成危害。
环指蛋白31抗体价格的优点:
①耐热、耐酸、耐碱、抗有机溶剂以及金属离子,稳定性好,室温下可以长期保存;
②制备简单,操作方便,可以进行批量;
③不必免疫动物,且可获得免疫动物所不能得到的“抗体”;
④可以反复使用;
⑤价格低廉。因此,设计、合成既具有类似生物抗体的高亲合性和高专一性,又具有耐热、耐酸、耐碱且又可以长期稳定的人工抗体,在部分领域替代生物抗体以进行仿生分子识别,或者完成一些生物抗体所不能完成的工作,具有重要的科学意义,在化学、生命科学和环境科学等方面具有广阔的应用前景
公司专业供应各种进口、国产一抗及二抗,品牌有R&D、Santa Cruz、Bipec、Millipore等国际知名品牌,品种多达7000多种,由于产品的数量众多,产品的宿主、抗原来源及应用范围(WB、IH(F/P)、FC、ELISA、IP、IF等)有所不同。
CHRNA4碱型乙酰胆碱受体α4抗体 规格: 0.1ml
PCDHGB1原钙粘蛋白γB1抗体 规格: 0.2ml
HPV33E7人类状瘤病毒33抗体 0.2ml
FLAGTag(CT)FLAGTag标签抗体(C端) 规格: 0.1ml
TBX1/Brachyury先心病相关蛋白TBX1抗体 规格: 0.2ml
Phospho-LIMK1(Thr508)/LIMK2(Thr505)磷酸化单丝氨酸蛋白激酶1/2抗体 规格: 0.1ml
HAUS4/C14orf9414号染色体开放阅读框94抗体 规格: 0.2ml
MouseAnti-humanIgG/PE-Cy3PE-Cy3标记的小鼠抗人IgG 规格: 0.1ml
Defensinβ1防御素β1抗体 规格: 0.1ml
IFNA21/IFNAF干扰素α21抗体 规格: 0.2ml 维生素
环指蛋白31抗体价格L-Lysine L-赖氨酸盐酸盐 25g 瓶
鲑鱼精DNA 10mg/ml 1ml 支
去内毒素质粒大量提取试剂盒 10T 盒
羊抗小鼠IgG-HRP 1ml 支
4×SDS-PAGE浓缩胶缓冲液(PH=6.8) 100ml 瓶
鸭脏器组织淋巴细胞分离液试剂盒 200ml/KIT 盒
4-Hydroxy-3-methoxybenzyl alcohol-Vanillicalcohol 香草醇 498-00-0 20mg
Protopanaxatriol 原人参三醇 34080-08-5 20mg
Haderacoside D 常春藤苷D 760961-03-3 20mg
Curcumin 姜黄素 458-37-7 20mg
海藻多糖 20mg
Estradiol β-雌二醇 50-28-2 100mg
英文名称 Anti-RNF31/HOIP
中文名称 环指蛋白31抗体价格
别 名 HOIL 1L interacting protein; HOIL-1-interacting protein; HOIL-1L interacting protein; HOIL1L interacting protein; HOIP; RING finger protein 31; RNF31; RNF31_HUMAN; ZIBRA; Zinc in between ring finger ubiquitin associated domain; Zinc in-between-ring-finger ubiquitin associated domain; Zinc in-between-RING-finger ubiquitin-associated domain protein; FLJ10111; FLJ23501
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Horse, Rabbit
产品类型 一抗
研究领域 细胞生物 染色质和核信号 信号转导 转录调节因子 表观遗传学
蛋白分子量 predicted molecular weight: 118kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human RNF31/HOIP
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 E3 ubiquitin-protein ligase component of the LUBAC complex which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation. LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex. Binds polyubiquitin of different linkage types.
Function : E3 ubiquitin-protein ligase component of the LUBAC complex which conjugates linear ('M-1'-linked) polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation. LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex. Binds polyubiquitin of different linkage types.
Subunit : Interacts with MUSK. Component of the LUBAC complex (linear ubiquitin chain assembly complex) which consists of SHARPIN, RBCK1 and RNF31. LUBAC has a MW of approximative 600 kDa suggesting a heteromultimeric assembly of its subunits. Associates with the TNF-R1 signaling complex (TNF-RSC) in a stimulation-dependent manner. Contains 1 UBA domain.
Subcellular Location : Cytoplasm.
Tissue Specificity : Expressed in both normal and transformed breast epithelial cell lines.
Similarity : Contains 1 IBR-type zinc finger.
Contains 3 RanBP2-type zinc fingers.
Contains 2 RING-type zinc fingers.
Contains 1 UBA domain.
环指蛋白31抗体价格具有高度的特异性,免疫组织化学正是利用了这一原理。先将组织或细胞中的某种化学物质提取出来,以此作为抗原或半抗原,通过免疫动物后获得特异性的抗体,再以此抗体去探测组织或细胞中的同类的抗原物质。由于抗原与抗体的复合物是无色的,因此还必须借助于组织化学的方法将抗原抗体结合的部位显示出来,以其达到对组织或细胞中的未知抗原进行定性,定位或定量的研究。
环指蛋白31抗体价格包括以下几个步骤:
1、制备抗原。
2、选择实验动物。
3、动物免疫。
4、试取血进行测试,看看是否成功免疫。
5、如果成功免疫,杀死实验动物,采集全部血清。
6、纯化出抗体。
7、鉴定抗体。包括纯度以及特异性。
环指蛋白31抗体价格的功能
抗体的主要功能是与抗原(包括外来的和自身的)相结合,从而有效地清除侵入机体内的微生物、寄生虫等异物,抗体(antibody)是一种应答抗原产生的、可与抗原特异性结合的蛋白质。每种抗体与特定的抗原决定基结合。这种结合可以使抗原失活,也可能无效但有时也会对机体造成病理性损害,如抗核抗体、抗双链DNA抗体、抗甲状腺球蛋白抗体等一些自身抗体的产生,对人体可造成危害。
环指蛋白31抗体价格的优点:
①耐热、耐酸、耐碱、抗有机溶剂以及金属离子,稳定性好,室温下可以长期保存;
②制备简单,操作方便,可以进行批量;
③不必免疫动物,且可获得免疫动物所不能得到的“抗体”;
④可以反复使用;
⑤价格低廉。因此,设计、合成既具有类似生物抗体的高亲合性和高专一性,又具有耐热、耐酸、耐碱且又可以长期稳定的人工抗体,在部分领域替代生物抗体以进行仿生分子识别,或者完成一些生物抗体所不能完成的工作,具有重要的科学意义,在化学、生命科学和环境科学等方面具有广阔的应用前景
公司专业供应各种进口、国产一抗及二抗,品牌有R&D、Santa Cruz、Bipec、Millipore等国际知名品牌,品种多达7000多种,由于产品的数量众多,产品的宿主、抗原来源及应用范围(WB、IH(F/P)、FC、ELISA、IP、IF等)有所不同。
CHRNA4碱型乙酰胆碱受体α4抗体 规格: 0.1ml
PCDHGB1原钙粘蛋白γB1抗体 规格: 0.2ml
HPV33E7人类状瘤病毒33抗体 0.2ml
FLAGTag(CT)FLAGTag标签抗体(C端) 规格: 0.1ml
TBX1/Brachyury先心病相关蛋白TBX1抗体 规格: 0.2ml
Phospho-LIMK1(Thr508)/LIMK2(Thr505)磷酸化单丝氨酸蛋白激酶1/2抗体 规格: 0.1ml
HAUS4/C14orf9414号染色体开放阅读框94抗体 规格: 0.2ml
MouseAnti-humanIgG/PE-Cy3PE-Cy3标记的小鼠抗人IgG 规格: 0.1ml
Defensinβ1防御素β1抗体 规格: 0.1ml
IFNA21/IFNAF干扰素α21抗体 规格: 0.2ml 维生素
环指蛋白31抗体价格L-Lysine L-赖氨酸盐酸盐 25g 瓶
鲑鱼精DNA 10mg/ml 1ml 支
去内毒素质粒大量提取试剂盒 10T 盒
羊抗小鼠IgG-HRP 1ml 支
4×SDS-PAGE浓缩胶缓冲液(PH=6.8) 100ml 瓶
鸭脏器组织淋巴细胞分离液试剂盒 200ml/KIT 盒
4-Hydroxy-3-methoxybenzyl alcohol-Vanillicalcohol 香草醇 498-00-0 20mg
Protopanaxatriol 原人参三醇 34080-08-5 20mg
Haderacoside D 常春藤苷D 760961-03-3 20mg
Curcumin 姜黄素 458-37-7 20mg
海藻多糖 20mg
Estradiol β-雌二醇 50-28-2 100mg
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环指蛋白31抗体价格
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