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- 保存条件:
冷藏
- 保质期:
长期
- 英文名:
Recombinant Human Interferon alpha/beta Receptor 2
- 库存:
958
- 供应商:
北京百奥莱博科技有限公司
特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博专业生产销*(代"售")重组人干扰素α/β受体2(IFNα/βR2)厂家现货,我公司供应的分子生物学试剂品类齐全,且具有优势价格,欢迎新老客户垂询订购。
名称:重组人干扰素α/β受体2(IFNα/βR2)厂家现货
规格:10μg|50μg|500μg|1mg
产地:国产|进口
品牌:百奥莱博
英文名:Recombinant Human Interferon alpha/beta Receptor 2
编号:JN1131
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Ile27-Lys243在C端带有Fc标签。
IFN-alpha/beta R2质量控制:>95%(还原性SDS-PAGE)
IFN-alpha/beta R2制剂:冻干品
IFN-alpha/beta R2保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
IFN-alpha/beta R2复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于IFN-alpha/beta R2:
Interferon α/β Receptor 2 (IFN-α/β R2) is a single-pass type I membrane protein which belongs to the type II cytokine receptor family. It complexes with IFN-α/β R1 to form the signaling receptor complex for the family of α and β IFN subtypes. By alternative splicing, IFN-α/β R2 can exist as a secreted soluble protein or as a type I membrane protein. IFN-α/β R2 is the principal ligand binding subunit of the receptor. Ligand binding is stabilized by the subsequent association with IFN-α/β R1, resulting in the formation of a signaling ternary receptor complex. IFNAR2 was detected in most lymphocytes, monocytes, and granulocytes, although IFNAR2 expression was higher in the monocytes and granulocytes than in the lymphocytes. Among the lymphocyte subsets, IFNAR2 showed high expression in natural killer (NK) cells and low expression in T lymphocytes. Isoform 1 and isoform 3 of IFNAR2 are directly involved in signal transduction due to their interaction with the TYR kinase, JAK1. Isoform 1 also interacts with the transcriptional factors, STAT1 and STAT2. Both forms are potent inhibitors of type I IFN activity.
想要了解更多关于重组人干扰素α/β受体2(IFNα/βR2)厂家现货的价格、品牌、厂家、说明书、促销信息,请和我们联系。此外我公司还销*(代"售")下面的产品:
·重组小鼠PDGFRα(血小板衍生生长因子受体α)
编号:JN1537
英文名称:Recombinant Mouse Platelet-derived growth factor receptor alpha
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Leu25-Glu524在C端带有Fc标签。
PDGF R alpha质量控制:>95%(还原性SDS-PAGE)
PDGF R alpha制剂:冻干品
PDGF R alpha保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
PDGF R alpha复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于PDGF R alpha:
Platelet-derived growth factor receptors (PDGFR) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF) family. The PDGF family consists of PDGF-A, -B, -C and -D, which form either homo- or heterodimers (PDGF-AA, -AB, -BB, -CC, -DD). The four PDGFs are inactive in their monomeric forms. PDGFs bind to the protein tyrosine kinase receptors PDGF receptor-α and -β. These two receptor isoforms dimerize upon binding the PDGF dimer, leading to three possible receptor combinations, namely -αα, -ββ and -αβ. PDGFRα and PDGFRβ are members of the class III RTK family. Inappropriate PDGFRα and PDGFRβ signaling has been linked to a number of proliferative disorders.
重组人干扰素α/β受体2(IFNα/βR2)厂家现货关键词:重组人IFNα/βR2,重组人干扰素α/β受体2,重组干扰素α/β受体2,重组人干扰素α/β受体2蛋白,JN1131
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重组人干扰素α/β受体2(IFNα/βR2)厂家现货关键词:重组人IFNα/βR2,重组人干扰素α/β受体2,重组干扰素α/β受体2,重组人干扰素α/β受体2蛋白,JN1131
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