北京重组人前梯度同源蛋白2(AG-2)说明书

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专注于生命科学和生物技术领域，致力于为客户提供包括北京重组人前梯度同源蛋白2(AG-2)说明书在内的一系列分子生物学试剂产品，并提供一系列相关的技术服务。

名称：北京重组人前梯度同源蛋白2(AG-2)说明书
规格：10μg|50μg|500μg|1mg
英文名：Recombinant Human Anterior Gradient Protein 2 Homolog
编号：JN0556
产地：国产|进口
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Arg21-Leu175在C端含有His标签。

AG-2质量控制：＞95%(还原性SDS-PAGE)

AG-2制剂：液体

AG-2保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于AG-2：
Anterior Gradient 2 (AGR2) is an 18-21 kDa member of the PDI family of enzymes. AGR2 is widely expressed in secretory cells, such as small intestine goblet, prostate epithelium, enteroendo*(代"c")rine cells, and multiple carcinoma cell types. AGR2 forms transient disulfide linkages with molecules destined for secretion, possibly aiding protein folding. Expression of AGR2 shows a positive correlation with expression of estrogen receptor in breast carcinoma and a negative correlation with expression of EGF receptor. Mature human AGR2 is 155 amino acids (aa) in length (aa 21 - 175). Cys81 is presumed to participate in intermolecular bond formation. Over aa 21 - 175, human AGR2 shares 94% aa identity with mouse AGR2.

更多有关北京重组人前梯度同源蛋白2(AG-2)说明书的价格及使用说明等，请联系我们的业务经理王欣女士咨询，我公司还销*(代"售")以下产品：

·重组人低密度脂蛋白受体(LDLR)
编号：JN0846
英文名称：Recombinant Human Low-Density Lipoprotein Receptor
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ala22-Arg788在C端含有His标签。

LDLR质量控制：＞95%(还原性SDS-PAGE)

LDLR制剂：冻干品

LDLR保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

LDLR复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于LDLR：
Low-Density Lipoprotein Receptor (LDLR) is a transmembrane glycoprotein that plays a critical role in cholesterol homeostasis. LDLR mediates blood cholesterol level by interacting with lipoprotein particles like LDL and VLDL. The extracellular domain of LDLR contains LDL receptor type A (ligand-binding) modules (LA repeats), epidermal growth factor-like modules, and LY repeats containing the YWTD consensus motif that are important in binding and releasing of ApoB-100 and ApoE in lipoprotein particles. The C terminal domain of LDLR inside the cell is required for the receptor internalization. Loss of function mutations in the LDLR gene causes Familial Hypercholesterolemia (FH).


北京重组人前梯度同源蛋白2(AG-2)说明书关键词：JN0556,重组人AG-2,重组前梯度同源蛋白2,重组人前梯度同源蛋白2蛋白


·重组人ALCAM(CD166)
编号：JN1650
英文名称：Recombinant Human CD166 Antigen
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Trp28-Ala526在C端带有Fc标签。

ALCAM/CD166质量控制：＞95%(还原性SDS-PAGE)

ALCAM/CD166制剂：冻干品

ALCAM/CD166保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

ALCAM/CD166复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于ALCAM/CD166：
Activated leukocyte cell adhesion molecule (ALCAM), also named as CD166 and MEMD, is a typeI transmembrane glycoprotein of immunoglobulin superfamily, which mediates homotypic and heterotypic interactions between cells. ALCAM is expressed on thymic epithelium, microvascular endothelium, activated lymphocytes and monocytes, and monocytederived dendritic cells. ALCAM mediates low-affinity adhesion with itself or the cysteine-rich scavenger receptor CD6 to regulate T cell development, immunological synapses(IS), and cell migration through endothelial junctions. ALCAM on thymic epithelia mediates adhesion to CD6 on CD4+CD8+ T cells. Adhesion of ALCAM expressing antigen presenting cells and CD6-expressing T cells stabilizes the early IS, while later it enhances CD3 effects on T cell proliferation, CD25 expression, and Th1 commitment. ALCAM may influence expression or adhesion of the neuronal adhesion molecule NCAML1, both in the developing retina and invasive melanoma.


北京重组人前梯度同源蛋白2(AG-2)说明书关键词：JN0556,重组人AG-2,重组前梯度同源蛋白2,重组人前梯度同源蛋白2蛋白

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