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- 详细信息
- 技术资料
- 保存条件:
冷藏
- 保质期:
长期
- 英文名:
Recombinant Human Brain-Specific Angiogenesis Inhibitor 3
- 库存:
822
- 供应商:
北京百奥莱博科技有限公司
特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博专注于生命科学和生物技术领域,致力于为客户提供包括北京现货重组人脑组织特异性血管生成抑制因子3(BAI3)供应在内的一系列分子生物学试剂产品,并提供一系列相关的技术服务。
名称:北京现货重组人脑组织特异性血管生成抑制因子3(BAI3)供应
规格:10μg|50μg|500μg|1mg
品牌:百奥莱博
编号:JN0562
英文名:Recombinant Human Brain-Specific Angiogenesis Inhibitor 3
产地:国产|进口
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Ala25-Thr880在C端含有His标签。
BAI3质量控制:>95%(还原性SDS-PAGE)
BAI3制剂:冻干品
BAI3保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
BAI3复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于BAI3:
Human Brain-Specific Angiogenesis Inhibitor 3 (BAI3) is a 177 kDa seven-span transmembrane (TM) protein, which is thought to be a member of the secretin receptor family. It is synthesized by neurons of the CNS and likely is a negative regulator of angiogenesis. BAI3 is 1498 amino acids in size. It contains three distinct regions: an N-terminal extracellular domain (ECD) (aa25-883), a 7-TM segment, and a C-terminal cytoplasmic region. The ECD contains four antiangiogenic TSP type 1 repeat (aa296-508), and one GSP domain (aa 816-867) that is likely used to cleave the ECD from the membrane-bound receptor. There is one altermate splice form that shows a deletion of aa 643-665. Over aa 25-880, human BAI3 shares 98% aa identity with mouse BAI3. BAI3 has been reported primarily in the brain, but is also localized to lung, testis, and pancreas. It might be involved in angiogenesis inhibition and suppression of glioblastoma.
想要了解更多关于北京现货重组人脑组织特异性血管生成抑制因子3(BAI3)供应的价格、品牌、厂家、说明书、促销信息,请和我们联系。此外我公司还销*(代"售")下面的产品:
·重组人白介素IL-16(白细胞介素16)
编号:JN0343
英文名称:Recombinant Human Interleukin-16
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备,目的基因编码的Met1-Ser130表达纯化而来。
IL-16质量控制:>95%(还原性SDS-PAGE)。
IL-16制剂:冻干品
IL-16保存:
冻干蛋白可在-20℃长期保存,室温也可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天。
复溶后建议分装冻存在-20℃,可保存3个月,应避免反复冻融。
IL-16复溶:
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存,避免反复冻融。
关于IL-16:
Interleukin-16 (IL-16) is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, human IL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4+ T cells. Human and murine IL-16 show significant cross-species reactivity.
北京现货重组人脑组织特异性血管生成抑制因子3(BAI3)供应关键词:JN0562,重组脑组织特异性血管生成抑制因子3,重组人脑组织特异性血管生成抑制因子3蛋白,重组人BAI3
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北京现货重组人脑组织特异性血管生成抑制因子3(BAI3)供应关键词:JN0562,重组脑组织特异性血管生成抑制因子3,重组人脑组织特异性血管生成抑制因子3蛋白,重组人BAI3
·重组人LOXL2(类赖*酰氧化酶2)(赖*酰氧化酶样蛋白2)
编号:JN1654
英文名称:Recombinant Human Lysyl Oxidase Homolog 2
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Gln26-Gln774在C端带Avi-His标签。
LOXL2质量控制:>95%(还原性SDS-PAGE)
LOXL2制剂:液体
LOXL2保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于LOXL2:
Lysyl oxidase homolog 2 is a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity. The N-terminus is poorly conserved and may imp*(代"a")rt additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. LOXL2 can also crosslink collagen type IV and hence influence the sprouting of new blood vessels. LOXL2 is an enzyme that is up-regulated in several types of cancer and is associated with a poorer prognosis. LOXL2 changes the structure of histonesand thus changes the shape of the cells, making it easier for the cancer cells to metastasize.
北京百莱博科技有限公司是分子生物学试剂产品的专业生产供应销*(代"售")商,恭候您的咨询选购北京现货重组人脑组织特异性血管生成抑制因子3(BAI3)供应。
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