重组人信号转导与转录激活因子5B(STAT5B)价格厂家

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专注于生命科学和生物技术领域，致力于为客户提供包括重组人信号转导与转录激活因子5B(STAT5B)价格厂家在内的一系列分子生物学试剂产品，并提供一系列相关的技术服务。

名称：重组人信号转导与转录激活因子5B(STAT5B)价格厂家
品牌：百奥莱博
英文名：Recombinant Human Signal Transducer and Activator of Transcription 5B
规格：10μg|50μg|500μg|1mg
编号：JN0882
产地：国产|进口
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Thr321在C端含有His标签。

STAT5B质量控制：＞95%(还原性SDS-PAGE)

STAT5B制剂：液体

STAT5B保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于STAT5B：
Signal Transducer and Activator of Transcription 5b (STAT5B) is a member of the STAT family of transcription factors. They are responsible for an array of cellular activities including regulating growth, survival, differentiation, motility, and the immune response. STAT5B mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. Signal transduction and activator of transcription 5 (STAT5) is a member of the Jak/STAT signal transduction pathway and is activated by a variety of cytokines (IL22, IL6). STAT5 has two isoforms (A and B) that share 93% amino acid identity and bind the DNA consensus site TTCN3GAA. STAT5 mediates cytokine signaling by acting as a signal transducer in the cytoplasm and, upon phosphorylation, translocates to the nucleus and activates transcription of specific genes. STAT5 is involved in a wide array of biological processes ranging from regulating apoptosis to adult mammary gland proliferation, differentiation and survival.

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重组人信号转导与转录激活因子5B(STAT5B)价格厂家关键词：重组信号转导与转录激活因子5B,重组人信号转导与转录激活因子5B,重组人STAT5B,JN0882,重组人信号转导与转录激活因子5B蛋白


·重组人脑组织特异性血管生成抑制因子3(BAI3)
编号：JN0562
英文名称：Recombinant Human Brain-Specific Angiogenesis Inhibitor 3
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ala25-Thr880在C端含有His标签。

BAI3质量控制：＞95%(还原性SDS-PAGE)

BAI3制剂：冻干品

BAI3保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

BAI3复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于BAI3：
Human Brain-Specific Angiogenesis Inhibitor 3 (BAI3) is a 177 kDa seven-span transmembrane (TM) protein, which is thought to be a member of the secretin receptor family. It is synthesized by neurons of the CNS and likely is a negative regulator of angiogenesis. BAI3 is 1498 amino acids in size. It contains three distinct regions: an N-terminal extracellular domain (ECD) (aa25-883), a 7-TM segment, and a C-terminal cytoplasmic region. The ECD contains four antiangiogenic TSP type 1 repeat (aa296-508), and one GSP domain (aa 816-867) that is likely used to cleave the ECD from the membrane-bound receptor. There is one altermate splice form that shows a deletion of aa 643-665. Over aa 25-880, human BAI3 shares 98% aa identity with mouse BAI3. BAI3 has been reported primarily in the brain, but is also localized to lung, testis, and pancreas. It might be involved in angiogenesis inhibition and suppression of glioblastoma.


重组人信号转导与转录激活因子5B(STAT5B)价格厂家关键词：重组信号转导与转录激活因子5B,重组人信号转导与转录激活因子5B,重组人STAT5B,JN0882,重组人信号转导与转录激活因子5B蛋白


·重组人转化生长因子β受体2(TGF-βR2)
编号：JN0869
英文名称：Recombinant Human Transforming Growth Factor-beta Receptor Type II
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Thr23-Asp159在C端带有Fc标签。

TGFβR2质量控制：＞95%(还原性SDS-PAGE)

TGFβR2制剂：冻干品

TGFβR2保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

TGFβR2复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于TGFβR2：
TGFβR2 is a single-pass type I membrane protein and contains one protein kinase domain. TGFBR2 exsits as a heterodimeric complex with another receptor protein and binds TGF-beta. Signals triggered through the TGF-beta receptor complex prompt various responses by the cell. One such response is to inhibit cell growth and division. Based on this action, the TGF-beta receptor type 2 is sometimes called a tumor suppressor. Defects in TGFBR2 have been associated with Marfan syndrome, Loeys-Deitz aortic aneurysm syndrome, Osler-Weber-Rendu syndrome and the development of various types of tumors.

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