Anti-SIGLEC8 Polyclonal Antibo

英文名称Rabbit SIGLEC8 Polyclonal Antibody别名AOS1;HSPC140;SUA1;UBLE1A应用WB稀释比例WB1:500-1:2000交叉反应Human,Mouse,Rat蛋白分子量54kDaGene ID27181保存Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment.储存液PBS with 0.02% sodium azide, 50% glycerol, pH7.3.纯化方法Affinity purification亚型IgG免疫原Recombinant protein of human SIGLEC8性状Lyophilized or LiquidSwiss ProtQ9NYZ4克隆类型Polyclonal Antibody来源Rabbit背景资料Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).