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- 保存条件:
-20°C
- 保质期:
1年
- 英文名:
2µg ($50) 10µg ($130) 1mg ($5200) 1 Shipped with Ice Packs BACK TO TOP CATALOGUE NUMBER CYT-034
- 库存:
大量
- 供应商:
上海沪震实业有限公司
- 规格:
2μg/10μg/1mg
CATALOGUE NUMBER
CYT-034
SYNONYMS
Interferon alpha 2b, IFNA, INFA2, MGC125764, MGC125765.INTRODUCTION
IFN-alpha is produced by macrophages and has antiviral activities. Interferon stimulates the production of two enzymes: protein kinase and an oligoadenylate synthetase.DESCRIPTION
Interferon-a 2b Human Recombinant produced in E.coli is a single, non-glycosylated, polypeptide chain containing 165 amino acids and having a molecular mass of 19269 Dalton. The Pegylated IFN-a 2b is produced by attaching a 20kDa mPEG-aldehyde to the N-terminal IFN alpha-2b.Interferon-a 2b is purified by proprietary chromatographic techniques.
SOURCE
Escherichia Coli.PHYSICAL APPEARANCE
Colorless, clear and transparent solution.
FORMULATION
IFN-a 2b is supplied in solution (1.48mg/ml) containing 20mM Acetate Buffer (pH 6.0), 0.8%NaCl and 0.005% Polysorbate 80.STABILITY
IFN alpha-2b PEG should be stored refrigerated at 2° to 8°C. Vials should be kept in their packaging to protect from light until the time of use.
Shaking and freezing should be avoided.
PURITY
Greater than 97.0% as determined by SEC-HPLC.
BIOLOGICAL ACTIVITY
The specific activity as determined in a viral resistance assay using VSV-WISH cells was found to be 3,000,000 IU/mg.
USAGE
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验CD20 分子 CD20 常用单克隆抗体或代号: B1,Leu16 主要表达细胞: B,FDC [B] 分子质量(kDa)和结构: p33(非糖基化穿膜磷蛋白) 功 能: Ca2+通道,调节B细胞活化和增殖 CD20 Aka L26 33kd phosphoprotein with 3 hydrophobic regions that traverse the cell
、DNA或RNA病毒、多聚肌苷酸多聚胞苷酸(Poly I-C)、多核苷酸等刺激物诱导下产生。IFN-α/β在pH2或pH11以及热(56℃)条件下仍稳定,而IFN-γ则很易丧失活性。 2.IFN-α/β的分子结构和基因 IFN-α和IFN-β基因均位于人9号染色体和小鼠4号染色体,并连锁在一起。IFN-α基因至少有20个,成串排列在一个区域,无内含子,同一种属IFN-α不同基因产物其氨基酸同原性≥80%。人和小鼠IFN-β基因只有一个,无内含子,与IFN-α基因连锁在一起。IFN-β与IFN
细胞分化增殖有重要作用。 (三)补体受体(CR) 大多数B细胞表面有能与C3b和C3d结合的受体,分别称为CRⅠ和CRⅡ(即CD35和CD21)。CRⅠ主要见于成熟B细胞,活化B细胞其密度明显增高,但进入分化晚期又下降。CR可与抗原和抗体及补体形成的免疫复合物结合,促进B细胞的活化,CRⅡ也是EB病毒的受体。 (四)细胞因子受体(CKR) 活化B细胞可表达多种细胞因子体,如IL-1、IL-2、IL-4、IL-5以及IFN-γ等受体,与相应因子结合可促进B细胞的增殖和分化
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