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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 免疫原:
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human HMGB1.
- 亚型:
Rabbit Ig
- 形态:
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 5 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
- 保存条件:
Store at -20°C.
- 克隆性:
多克隆抗体
- 标记物:
见下方详细说明
- 适应物种:
H, M, R
- 宿主:
Rabbit
- 应用范围:
E, WB, IHC
- 浓度:
见详细说明信息
- 靶点:
HMGB1
- 抗体英文名:
HMGB1 Antibody
- 抗体名:
HMGB1 Antibody
- 规格:
0.1 mg
HMGB1 Antibody产品详细介绍:
| 产品名称: | HMGB1 Antibody |
| 说明书: | http://www.abbiotec.com/antibodies/hmgb1-antibody【参考图片】 |
| 货号: | 250508 |
| 规格: | 0.1 mg |
| 产品描述: | The HMG (high mobility group) proteins are nonhistone chromosomal proteins. High mobility group protein B1 (HMGB1) is an abundant component of all mammalian nuclei. HMGB1 binds preferentially single-stranded DNA and unwinds double-stranded DNA. |
| 克隆类型: | Rabbit Polyclonal Antibody |
| 亚型: | Rabbit Ig |
| 免疫原: | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human HMGB1. |
| 适用物种: | H, M, R |
| 应用范围: | E, WB, IHC |
| 应用说明: | E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500 |
| 别名: | High mobility group protein B1; High mobility group protein 1; HMG-1; HMGB1; HMG1 |
| 形态: | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 5 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
| 保存条件: | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献: |
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文献和实验Fluorescent Biosensors for the Detection of HMGB1 Release
During necrosis and following some instances of apoptosis (in particular in the absence of a proficient phagocytic system), the nonhistone chromatin component high-mobility group box 1 (HMGB1) is released in the extracellular space. In vivo
因为journal club要讲文章 顺便儿拿来和大家讨论下 Hmgb1调节TLR4介导的angiogenesis 最近才开始关注这个蛋白。这篇文章已经在线发表在atvb上,由中山医眼科中心完成的工作。 Hmgb1不仅可以作为一种nuclear factor, 而且还可以作为cytokine来介导感染引起的炎症,免疫损伤。Hmgb1已经在sepsis, arthritis, 肿瘤和其他多种疾病中明确了其作用。Hmgb1可以结合tlr2/4,并且通过MyD88依赖性信号通路促进
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
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