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- 详细信息
- 文献和实验
- 技术资料
- 亚型:
mouse IgG2a
- 形态:
Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
- 保存条件:
Store at 4°C.
- 克隆性:
单克隆
- 标记物:
见下方详细说明
- 适应物种:
H
- 保质期:
1-2年
- 目录编号:
251024
- 级别:
超纯
- 库存:
大量
- 供应商:
Abbiotec
- 宿主:
Mouse
- 应用范围:
FC
- 浓度:
见详细说明信息
- 靶点:
CD44 (HI44a)
- 抗体英文名:
CD44 (HI44a) Antibody
- 抗体名:
CD44 (HI44a) Antibody
- 规格:
2 ml
CD44 (HI44a) Antibody产品详细介绍:
| 产品名称: | CD44 (HI44a) Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 251024 |
| 规格: | 2 ml |
| 产品描述: | The CD44 (HI44a) antibody recognizes a highly glycosylated 80-90 kDa type-I transmembrane cell surface protein, which is the receptor for hyaluronic acid, also called phagocytic glycoprotein-1 (Pgp-1). CD44 antigen is widely expressed on most cell types including leukocytes, erythrocytes, endothelial cells and epithelial cells, but not on platelets. CD44 is involved in leukocyte attaching and rolling on endothelial cells, homing to peripheral lymphoid organs and sites of inflammation, and leukocyte aggregation. |
| 克隆类型: | Mouse Monoclonal Antibody, FITC-conjugated Antibody |
| 亚型: | mouse IgG2a |
| 免疫原: | |
| 适用物种: | H |
| 应用范围: | FC |
| 应用说明: | FC with whole blood: 100 μl blood + 20 μl antibody; FC with cells: 10E6 cells + 20 μl antibody. FC: 1:200-1:1,000 |
| 别名: | CD44; CD44 antigen; Phagocytic glycoprotein I; PGP-I; HUTCH-I; Extracellular matrix receptor III; ECMR-III; GP90 lymphocyte homing/adhesion receptor; Hermes antigen; Hyaluronate receptor; Heparan sulfate proteoglycan; Epican; CDw44 |
| 形态: | Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件: | Store at 4°C. Product is guaranteed 6 months from the date of shipment. |
| 参考文献: |
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文献和实验CD44/CD44R 分子 CD44 常用单克隆抗体或代号: GRHL1,Hermes,F10- 44- 2(Pgp- 1H- CAM,ECM- RⅢ) 主要表达细胞: Leu,上皮,Fb,RBC[AS] 分子质量(kDa)和结构: gp80- 95 功 能: 粘附ECM,T细胞活化,淋巴细胞归位受体,归位到HEV CD44R 常用单克隆抗体或代号: FM11,24
对CD44的研究时间较长、较深入亦较广泛。已知其为分布极为广泛的细胞表面跨膜糖蛋白,主要参与异质性粘附,即肿瘤细胞与宿主细胞和宿主基质的粘附,异质性粘附在肿瘤细胞侵袭转移中起促进作用。 人类CD44基因位于11号染色体短臂,全长约50kb,共由20个高度保守的外显子组成,每个外显子长度70-210bp不等,中间由长短不一的内含子分隔。CD44基因的20个外显子按照转录方式不同可分为组成型外显子(C)和变异型拼接外显子(V)两大类。组成型外显子共有10个,存在
PCR Analysis of CD44 Variants in Tumors
The CD44 molecule is a transmembrane glycoprotein, it is an acidic, sul fated protein that contains multiple phosphoserine residues and several intrachain disulfide bonds. It is essentially composed of a 37-kDa protein core highly glycosylated
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