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- 详细信息
- 文献和实验
- 技术资料
- 亚型:
mouse IgG1
- 形态:
Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
- 保存条件:
Store at 4°C.
- 克隆性:
单克隆
- 标记物:
见下方详细说明
- 适应物种:
H
- 保质期:
1-2年
- 目录编号:
251067
- 级别:
超纯
- 库存:
大量
- 供应商:
Abbiotec
- 宿主:
Mouse
- 应用范围:
FC
- 浓度:
见详细说明信息
- 靶点:
CD22 (HIB22)
- 抗体英文名:
CD22 (HIB22) Antibody
- 抗体名:
CD22 (HIB22) Antibody
- 规格:
2 ml
CD22 (HIB22) Antibody产品详细介绍:
| 产品名称: | CD22 (HIB22) Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 251067 |
| 规格: | 2 ml |
| 产品描述: | The CD22 (HIB22) antibody recognizes a 130-140 kDa type-I transmembrane glycoprotein that is a B cell restricted antigen. CD22 antigen is expressed in the cytoplasm of pro-B and pre-B cells, and on the surface of mature B lymphocytes. CD22 expression is increased after activation and lost at the terminal stage of B cell differentiation. Most B cell leukemias and lymphomas also express CD22. It is not expressed in T cells, monocytes and granulocytes. CD22 is an early marker for B-ALL and hairy-cell leukemia diagnostic. CD22 is an adhesion molecule that amplifies the signal of B cell activation. CD22 ligands are CD45RO antigen on T cells and CD75 antigen on B cells participating in the homotopic interaction of T and B cells. |
| 克隆类型: | Mouse Monoclonal Antibody, PE-conjugated Antibody |
| 亚型: | mouse IgG1 |
| 免疫原: | |
| 适用物种: | H |
| 应用范围: | FC |
| 应用说明: | FC with whole blood: 100 μl blood + 20 μl antibody; FC with cells: 10E6 cells + 20 μl antibody. FC: 1:200-1:1,000 |
| 别名: | B-cell receptor CD22; Sialic acid-binding Ig-like lectin 2; Siglec-2; Leu-14; B-lymphocyte cell adhesion molecule; BL-CAM; CD22; SIGLEC2 |
| 形态: | Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件: | Store at 4°C. Product is guaranteed 6 months from the date of shipment. |
| 参考文献: | Schlossman S. et al., eds. 1995. Leucocyte Typing V: White Cell Differentiation Antigens. P246, Oxford University Press, New York |
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文献和实验CD22 分子 CD22 常用单克隆抗体或代号: B3,HD39,Leu14,SHCL- 1,HC2 (BL- CAM) 主要表达细胞: B [B] 分子质量(kDa)和结构: gp130/140,髓鞘(磷)脂相关蛋白类似物(MAG)(IgSF) 功 能: 与CD45RO、CD75结合,B细胞粘附到M、红细胞,介导B- B、B- T细胞相互作用 CD22 Aka B
Anti-CD22 Onconase: Preparation and Characterization
Antibodies can be conjugated to effector molecules to derive targeted therapeutics with properties such as cell-specific cytotoxicity. The murine anti-CD22 antibody RFB4 linked to a member of the ribonuclease A superfamily, Onconase (Onc
CD40 / CD22 白细胞分化抗原及其功能 CD40 属于TNFR-SF,胞膜外区有4个富含牛胱氨酸重复序列(图6―2),表达于APC细胞,以及某些上皮细胞、内皮细胞、成纤维细胞、淋巴样并指细胞、FDC以及活化的单核细胞。浆细胞不表达CD40分子。 CD40结合CD40L(CDl54),胞质区Thr234是CD40介导信号转导关键的氨基酸残基。CD40-CD40L相互作用是B细胞活化中第二信号的主要来源,而且对于T
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