- ￥3000 - 3999
- Abbiotec
- 美国
- 250214
- 2025年07月08日
- E
- Mouse
- H
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Human plasma C1s Proenzyme
- 亚型：
Mouse IgG1/k
- 形态：
Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
- 保存条件：
Store at 4°C.
- 克隆性：
单克隆抗体
- 标记物：
见下方详细说明
- 适应物种：
H
- 宿主：
Mouse
- 应用范围：
E
- 浓度：
见详细说明信息
- 靶点：
C1s (49)
- 抗体英文名：
C1s (49) Antibody
- 抗体名：
C1s (49)抗体
- 规格：
0.2 mg
C1s (49) Antibody产品详细介绍：
| 产品名称： | C1s (49) Antibody |
| 说明书： | http://www.abbiotec.com/antibodies/c1s-49-antibody【参考图片】 |
| 货号： | 250214 |
| 规格： | 0.2 mg |
| 产品描述： | C1s proenzyme is a 79.8 kDa glycoprotein produced primarily by hepatocytes but also by other cells. The proenzyme is produced as a single-chain polypeptide of 688 aa. Upon activation the peptide is cleaved between R437 and I438 giving the activated enzyme consisting of two disulfide-linked chains, A chain (52.2 kDa) and B chain (27.7 kDa). The Ca-dependent catalytic subunit of the C1 complex (C1q, C1r, C1s) comprises of two C1s and two C1r molecules and this serine protease tetramer is responsible for the initial steps in the classical complement pathway, cleavage of C4 and C2. This antibody is specific for C1s proenzyme and activated free C1s and C1s in complex with C1 inhibitor. |
| 克隆类型： | Mouse Monoclonal Antibody |
| 亚型： | Mouse IgG1/k |
| 免疫原： | Human plasma C1s Proenzyme |
| 适用物种： | H |
| 应用范围： | E |
| 应用说明： | Product Cat. No. 250214 reacts in ELISA when tested with activated C1s enzyme directly coated onto the microtiter well or in sandwich ELISA in combination with a polyclonal antibody in coat. E: 1:1,000 |
| 别名： | C1 Esterase |
| 形态： | Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography. |
| 保存条件： | Store at 4°C. Product is guaranteed 6 months from the date of shipment. |
| 参考文献： |
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文献和实验补体成分 C1(C1q/C1r/C1s) 补体成分：C1q 血清浓度(μg/ml)：75 分子量(kDa)：410 亚单位(链)及分子量(kDa)：A：24各6条B：23各6条C：22各6条 生物学活性：识别IgG、IgMFc的补体结合点 补体成分：C1r 血清浓度(μg/ml)：50 分子量(kDa)：85
Conjugation of Antibody to HRP
:EDTA Add 0.25 g NaOH pellets to this solution to neutralize to approximately pH 7.0 Add to antibody solution at 6.49 ml/ml SATA. Gently stir for 30 minutes at room temperature. Equilibrate column with PBS:EDTA. Desalt thiolated antibody
associates with the recognition protein C1q. The C1 complex circulates in serum as a zymogen and is activated upon binding of C1q to appropriate targets, such as antigen–antibody complexes. This property is used for the purification of C1r and C1s from human
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