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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human PDL-1.
- 亚型:
Rabbit Ig
- 形态:
Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
- 保存条件:
Store at -20°C.
- 克隆性:
多克隆
- 标记物:
见下方详细说明
- 适应物种:
H, M, R
- 保质期:
1-2年
- 抗原来源:
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human PDL-1.
- 目录编号:
253699
- 级别:
超纯
- 库存:
大量
- 供应商:
Abbiotec
- 宿主:
Rabbit
- 应用范围:
E, WB, IHC, IF
- 浓度:
见详细说明信息
- 靶点:
PDL-1
- 抗体英文名:
PDL-1 Antibody
- 抗体名:
PDL-1 Antibody
- 规格:
0.1 mg
PDL-1 Antibody产品详细介绍:
| 产品名称: | PDL-1 Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 253699 |
| 规格: | 0.1 mg |
| 产品描述: | Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. PDL-1 is a B7-related protein that inhibits cell-mediated immune responses by reducing the secretion of IL-2 and IL-10 from memory T cells. This suggests that PDL-1 may be useful in reducing allogenic CD4+ memory T-cell responses to endothelial cells, thereby reducing the likelihood of host immune responses to allografts. At least two isoforms of PDL-1 are known to exist; this antibody is specific to the larger isoform. PDL-1 antibody has no cross-reactivity to PDL-2. |
| 克隆类型: | Rabbit Polyclonal Antibody |
| 亚型: | Rabbit Ig |
| 免疫原: | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human PDL-1. |
| 适用物种: | H, M, R |
| 应用范围: | E, WB, IHC, IF |
| 应用说明: | E: 1:500-1:1,000; WB: 1:1,000-1:2,000; IHC: 1:100-1:500; IF: 1:20-1:50 |
| 别名: | PDL-1; Programmed cell death 1 ligand 1; programmed death ligand 1; PD-L1; B7-H1; PDCD1 ligand 1; B7 homolog 1; CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1 |
| 形态: | Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography. |
| 保存条件: | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献: |
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