万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant soluble human TNF-R2-Fc fusion protein
- 亚型:
mouse IgG2a
- 形态:
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
- 保存条件:
Store at -20°C.
- 克隆性:
单克隆抗体
- 标记物:
见下方详细说明
- 适应物种:
H
- 宿主:
Mouse
- 应用范围:
E, FC
- 浓度:
见详细说明信息
- 靶点:
TNF-R2
- 抗体英文名:
TNF-R2 Antibody
- 抗体名:
TNF-R2抗体
- 规格:
0.1 mg
TNF-R2 Antibody产品详细介绍:
| 产品名称: | TNF-R2 Antibody |
| 说明书: | http://www.abbiotec.com/antibodies/tnf-r2-antibody【参考图片】 |
| 货号: | 250107 |
| 规格: | 0.1 mg |
| 产品描述: | Tumor necrosis factor receptor 2 (TNF-R2) is a high-affinity receptor for TNF-alpha and a low-affinity receptor for lymphotoxin-alpha. TNF-R2 has two isoforms produced by alternative splicing: a cell membrane and a secreted form. The latter blocks TNF-alpha-induced apoptosis, which suggests that this isoform regulates TNF-alpha function by antagonizing its biological activity. A soluble fragment of TNF-R2 (Enbrel, Immunex and Wyeth-Ayerst) is used as treatment of moderate and severe rheumatoid arthritis. This antibody recognizes human TNF-R2 in ELISA and flow cytometry. |
| 克隆类型: | Mouse Monoclonal Antibody |
| 亚型: | mouse IgG2a |
| 免疫原: | Recombinant soluble human TNF-R2-Fc fusion protein |
| 适用物种: | H |
| 应用范围: | E, FC |
| 应用说明: | E: 5 mg/ml; FC: 1 mg/0.1 ml |
| 别名: | Tumor necrosis factor receptor superfamily member 1B; Tumor necrosis factor receptor 2; TNF-R2; Tumor necrosis factor receptor type II; p75; p80 TNF-alpha receptor; CD120b antigen; Etanercept; Tumor necrosis factor-binding protein 2; TNFRSF1B; TNFBR, TNFR2 |
| 形态: | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
| 保存条件: | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献: |
ABBIOTEC产品提供质量保证,提供完善的售后和技术支持,ABBIOTEC产品正品包装:
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Tumor necrosis factor-α (TNF-α) is a cytokine (CK) that possesses a wide variety of biological activities, including potent antitumor activities (1 ) and immunomodulatory properties mediated through its binding to two TNF receptors (p55
The ICH S5(R2) Guideline for the Testing of Medicinal Agents
Relying on previous regulatory guidelines from multiple countries, the ICH S5(R2) guideline outlines the preclinical safety studies needed for registration of new medicinal products in the member countries (European Union, Japan
AntibodyCytokine Fusion Proteins with Members of the TNF-Family
The generation of antibody fusion proteins for target-directed delivery of cytokines constitutes a promising immunotherapeutic approach. The fusion of recombinant antibodies to members of the TNF-family that differ clearly in their soluble
技术资料暂无技术资料 索取技术资料










