ARRDC1 Antibody
Cat#:PL0306079
Isotype:Rabbit Polyclonal IgG
Immunogen:Peptide derived from huamn ARRDC1.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
ARRDC1, ARRDC2 (which exists as multiple alternatively spliced isoforms), ARRDC4 and ARRDC5 are arrestin domain-containing proteins that are encoded by genes which map to human chromosomes 9, 15 and 19. Chromosome 9, on which the ARRDC1 gene is localized, contains 145 million base pairs and comprises 4% of the human genome, encoding nearly 900 genes. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster. The ARRDC2 and ARRDC5 genes map to chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. Unlike other ARRDC genes, the ARRDC4 gene maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome.
Alternate Names:
ARRD1_HUMAN; ARRDC 1; ARRDC1; Arrestin domain containing 1; Arrestin domain containing protein 1; Arrestin domain-containing protein 1.
Specificity Reaction:Hu, Mo, Rat, Dog, Cow, Hor,
Application Notes:WB: 1:100-500 E: 1:500-1000 IP: 1:20-100 IHC: 1:100-500 IF: 1:100-500
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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