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581-05-5
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文献和实验The Prohormone Theory and the Proprotein Convertases: It Is All About Serendipity
me to discover that the sequence of β-melanocyte-stimulating hormone was contained within that γ and β-lipotropins and could be released from the latter by limited endoproteolysis. This prohormone theory became the leitmotiv of my career as a clinician/scientist
with the same efficiency that the molecules of RNA target in each sample. We have also been able to detect expression of this receptor in all studied tissues, which is consistent with the pleiotropic nature of growth hormone in fish (20 �23 ). The expression
睾丸曲细精管的生精过程和间质细胞的睾酮分泌均受下丘脑-垂体的调节。下丘脑分泌的GnRH经垂体门脉到达腺垂体,促进腺垂体促性腺激素细胞合成和分泌卵泡细胞刺激素(follicle-stimulating hormone, FSH)和黄体生成素(luteinizing hormone, LH)。LH主要作用于间质细胞,而FSH主要作用于生精细胞与支持细胞。动物实验证明,幼年动物摘除垂体后,导致睾丸及附性器官不能发育成熟,呈幼稚状态。如果把成年雄发生动物垂体摘除后,睾丸发生萎缩,生精细胞和间质
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