Brefeldin A

概述

• 产品名称
  Brefeldin A
• 描述
  Inhibitor of ADP-ribosylation factor
• 别名
  • Ascotoxin
  • BFA
  • Cyanein
  • Decumbin
• 生物学描述
  Reversible inhibitor of protein translocation from the endoplasmic reticulum to the Golgi apparatus. Inhibits binding of the cytosolic coat protein, β-COP and ADP-ribosylation factor (ARF) to Golgi membranes and inhibits GDP-GTP exchange.
• 纯度
  > 99%

性能

• 化学名称
  (1R,2E,6S,10E,11aS,13S,14aR)-1,13-Dihydroxy-6-methyl-1,6,7,8,9,11a,12,13,14,14a-decahydro-4H-cyclopenta[f]oxacyclotridecin-4-one
• 分子量
  280.36
• 化学结构
  
• 分子式
  C₁₆H₂₄O₄
• CAS编号
  20350-15-6
• PubChem识别号
  5287620
• 存放说明
  Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
• 溶解度概述
  Soluble in DMSO to 50 mM
• 处理

  Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

  Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

• SMILES
  O[C@@H]1C[C@H]2[C@H](O)C=CC(=O)O[C@@H](C)CCCC=C[C@@H]2C1
• 来源

  Eupenicillium brefeldianum