Lovastatin (Mevinolin)

概述

• 产品名称
  Lovastatin (Mevinolin)
• 描述
  Potent HMG-CoA reductase inhibitor
• 别名
  • Mevinolin
• 生物学描述
  Potent, competitive HMG-CoA reductase inhibitor (K_i = 0.6 nM). Blood-brain barrier permeable. Inhibits in vivo and in vitro cholesterol biosynthesis. Also reduces α-synuclein levels in vitro and in vivo.
• 纯度
  > 98%

性能

• 化学名称
  (2S)-(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl-2-methyl butanoate
• 分子量
  404.54
• 化学结构
  
• 分子式
  C₂₄H₃₆O₅
• CAS编号
  75330-75-5
• 存放说明
  Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
• 溶解度概述
  Soluble in DMSO to 100 mM and in ethanol to 50 mM
• 处理

  Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

  Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

• 来源

  Synthetic