Z-VAD-FMK

概述

• 产品名称
  Z-VAD-FMK
• 描述
  Irreversible general caspase inhibitor
• 生物学描述
  An irreversible general caspase inhibitor. Non cell-permeable and does not require pretreatment with an esterase. Useful for non-cellular in vitro studies involving isolated, purified or recombinant caspase enzymes. Cell-permeable version also available - Z-VAD (OMe)-FMK ab120487.
• 纯度
  > 97%

性能

• 分子量
  453.46
• 化学结构
  
• 分子式
  C₂₁H₂₈FN₃O₇
• 序列
  VAD (Modifications: N-terminal benzyloxycarbonyl; C-terminal FMK)
• PubChem识别号
  5497170
• 存放说明
  Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
• 溶解度概述
  Soluble in DMSO to 20 mM
• 处理

  Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

  Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

• SMILES
  FCC(=O)C(CC(=O)O)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C
• 来源

  Synthetic