北京重组人MERTK(酪氨酸蛋白激酶Mer)品牌

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京重组人MERTK(酪*酸蛋白激酶Mer)品牌的品牌：百奥莱博，是优质的分子生物学试剂产品，用于科研实验，本产品质量好，且极具价格优势，深为用户称道，了解更多重组人MERTK(酪*酸蛋白激酶Mer)等分子生物学试剂产品请联系我司咨询订购。

名称：北京重组人MERTK(酪*酸蛋白激酶Mer)品牌
规格：10μg|50μg|500μg|1mg
编号：JN1278
产地：国产|进口
英文名：Recombinant Human Tyrosine-protein kinase Mer
品牌：百奥莱博
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Met177-Ala499在C端含有His标签。

MERTK质量控制：＞95%(还原性SDS-PAGE)

MERTK制剂：冻干品

MERTK保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

MERTK复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于MERTK：
Tyrosine-protein kinase Mer (MERTK) is a single-pass type I membrane protein which belongs to the MER/AXL/TYRO3 receptor kinase family. MERTK include two fibronectin type-III domains, two Ig-like C2-type domains, and one tyrosine kinase domain. It can’t be expressed in normal B- and T-lymphocytes, but it is usually expressed in numerous neoplastic B- and T-cell lines.MERTK could regulate many physiological processes, such as cell survival, migration, differentiation. It was demonstrated that the MERTK plays critical role in the engulfment and efficient clearance of apoptotic cells, platelet aggregation, and cytoskeleton reorganization. Not only these, it also plays an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3. In addition, MERTK could regulate rod outer segments fragments phagocytosis in the retinal pigment epithelium (RPE)， deficiency in MERTK are the cause of retinitis pigmentosa.

想要了解更多关于北京重组人MERTK(酪*酸蛋白激酶Mer)品牌的价格、品牌、厂家、说明书、促销信息，请和我们联系。此外我公司还销*(代"售")下面的产品：

·重组人u-Plasminogen Activator
编号：JN0547
英文名称：Recombinant Human Urokinase-Type Plasminogen Activator
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ser21-Leu431在C端含有His标签。

u-Plasminogen Activator质量控制：＞95%(还原性SDS-PAGE)

u-Plasminogen Activator制剂：液体

u-Plasminogen Activator保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于u-Plasminogen Activator：
Recombinant Human Urokinase-Type Plasminogen Activator is a serine protease, which specifically cleaves the zymogen plasminogen to form the active enzyme plasmin. Urokinase-Type Plasminogen Activator is a potent marker of invasion and metastasis in many human cancers associated with breast, colon, stomach, bladder, brain, ovary and endometrium. Human Urokinase-Type Plasminogen Activator is initially synthesized as 431 amino acid precursor with a N-terminal signal peptide residues. The single chain molecule is processed into a disulfide-linked two-chain molecule. There exists two forms A chain, the long A chain contains an EGF-like domain that is responsible for binding of the uPA receptor. The B chain corresponds to the catalytic domain.



北京重组人MERTK(酪*酸蛋白激酶Mer)品牌关键词：重组人MERTK,重组MERTK,JN1278,重组人酪*酸蛋白激酶Mer,重组人MERTK蛋白

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北京重组人MERTK(酪*酸蛋白激酶Mer)品牌关键词：重组人MERTK,重组MERTK,JN1278,重组人酪*酸蛋白激酶Mer,重组人MERTK蛋白


·重组人PRAP1(酸性富脯*酸蛋白1)
编号：JN0810
英文名称：Recombinant Human Proline-Rich Acidic Protein 1
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Val21-Gln151在C端含有His标签。

PRAP1质量控制：＞95%(还原性SDS-PAGE)

PRAP1制剂：冻干品

PRAP1保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

PRAP1复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于PRAP1：
Proline-rich acidic protein 1, also known as Uterine-specific proline-rich acidic protein, UPA and PRAP1, is a secreted protein. PRAP1 is abundantly expressed in the epithelial cells of the liver, kidney, gastrointestinal tract and cervix. PRAP1 is up-regulated by butyrate, trichostatin A and 5-aza-2 deoxycytidine. PRAP1 may play an important role in maintaining normal growth homeostasis in epithelial cells. PRAP1 is suppressed through epigenetic mechanisms involving histone deacetylation and methylation. PRAP1 has been shown to cause cell growth inhibition in cancer cell lines.

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