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- 保存条件:
冷藏
- 保质期:
长期
- 英文名:
Recombinant Human OX40L receptor
- 库存:
733
- 供应商:
北京百奥莱博科技有限公司
特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博专业生产销*(代"售")北京现货重组人OX40(TNFRSF4)(CD134)(N端Fc标签)供应,我公司供应的分子生物学试剂品类齐全,且具有优势价格,欢迎新老客户垂询订购。
名称:北京现货重组人OX40(TNFRSF4)(CD134)(N端Fc标签)供应
产地:国产|进口
品牌:百奥莱博
英文名:Recombinant Human OX40L receptor
编号:JN0489
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Leu29-Ala216在N端带有Fc标签。
OX40/TNFRSF4/CD134质量控制:>95%(还原性SDS-PAGE)
OX40/TNFRSF4/CD134制剂:冻干品
OX40/TNFRSF4/CD134保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
OX40/TNFRSF4/CD134复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于OX40/TNFRSF4/CD134:
OX40, also termed CD134 and TNFRSF4, is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis of effector and memory T cells. OX40 is expressed on CD4+ and CD8+ T cells upon engagement of the TCR by antigen presenting cells along with co-stimulation by CD40-CD40 Ligand and CD28-B7. The interaction between OX40 and OX40 ligand (OX40L) will occur when activated T cells bind to professional antigen-presenting cells (APCs). The T-cell functions, including cytokine production, expansion, and survival, are then enhanced by the OX40 costimulatory signals. OX40 signals are critical for controlling the function and differentiation of Foxp3+ regulatory T cells. OX40-OX40L interaction regulates T-cell tolerance, peripheral T-cell homeostasis, and T-cell-mediated inflammatory diseases.
除北京现货重组人OX40(TNFRSF4)(CD134)(N端Fc标签)供应外,我公司正在打折促销以下产品:
·重组人胶质细胞源性神经营养因子(GDNF)
编号:JN1130
英文名称:Recombinant Human Glial Cell Line-Derived Neurotrophic Factor
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Phe20-Ile211在C端含有Fc标签和His标签
GDNF质量控制:>95%(还原性SDS-PAGE)
GDNF制剂:冻干品
GDNF保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
GDNF复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于GDNF:
Glial Cell Line-Derived Neurotrophic Factor (GDNF) is a disulfide-linked homodimeric glycoprotein that belongs to the TGF-β superfamily. It has been shown to promote the survival of various neuronal subpopulations in both the central as well as the peripheral nervous systems at different stages of their development. Human GDNF cDNA encodes a 211 amino acid residue prepropeptide that is processed to yield a dimeric protein. Mature human GDNF was predicted to contain two 134 amino acid residue subunits. Cells known to express GDNF include Sertoli cells, type 1 astrocytes, Schwann cells, neurons, pinealocytes and skeletal muscle cells. Mutations in this gene may be associated with Hirschsprung disease.
北京现货重组人OX40(TNFRSF4)(CD134)(N端Fc标签)供应关键词:重组人OX40,N端Fc标签,重组人CD134,JN0489,重组人TNFRSF4
·重组小鼠白介素IL-13(C端带His标签)
编号:JN0390
英文名称:Recombinant Mouse Interleukin-13
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物表达系统制备,目的基因编码的Ser26-Phe131在C端含有His标签。
IL-13质量控制:>95%(还原性SDS-PAGE)。
IL-13制剂:冻干品
IL-13保存:
冻干蛋白可在-20℃长期保存,室温也可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天。
复溶后建议分装冻存在-20℃,可保存3个月,应避免反复冻融。
IL-13复溶:
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存,避免反复冻融。
关于IL-13:
Mouse interleukin 13 (mIL-13) is a pleiotropic cytokine produced by activated Th2 cells. IL-13 induces B cell proliferation and immunoglobin production. It contains a four helical bundle with two internal disulfide bonds. Mouse IL13 shares 58% sequence identity with human protein and exhibits cross-species activity. IL13 signals via receptor IL13R (type2, IL4R) and activates STAT-6. IL13 initially binds IL-13Rα1 with low affinity and triggers association of IL4Rα, generating a high affinity heterodimeric receptor IL13R and eliciting downstream signals. IL13 also binds IL-13Rα2 with high affinity, which plays a role in a negative feedback system of IL13 signaling. IL13 is an important mediator of allergic inflammation and disease.
北京现货重组人OX40(TNFRSF4)(CD134)(N端Fc标签)供应关键词:重组人OX40,N端Fc标签,重组人CD134,JN0489,重组人TNFRSF4
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我公司正在优惠促销分子生物学试剂等系列产品,期待您的咨询选购北京现货重组人OX40(TNFRSF4)(CD134)(N端Fc标签)供应。
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文献和实验酶蛋白量较少而目的蛋白量相对较多(约占Pp总分泌蛋白量的30-90%,如人乙酰胆碱酯酶B变异链的含量占到90%,使下游纯化更易进行。当诱导AOX1时,转化子不能同时高水平产生酒精氧化酶和外源蛋白,与野生型Mut+比较,Mut-细胞对氧的要求亦较低,生长也较慢。为解决这个问题,Jeffrey等用甲醇加甘油混合饲养,得到了255mg/L的CD40配体(CD40L)。但由于甘油可部分阻遏aoxl启动子,蛋白表达可能并不处于最佳水平。Sreekrishna等最近运用山梨醇和甲醇混合批量饲养发酵,在不到4个星期
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