- ￥630 - 2415
- Elabscience
- E-AB-20849
- 湖北武汉
- 2025年08月20日
- Rabbit
- Human;Mouse;Rat
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- 详细信息
- 文献和实验
- 技术资料
- 抗体名：
Phospho-CREB1 (Ser133) 多克隆抗体_货号:E-AB-20849_修饰性抗体
- 抗体英文名：
Phospho-CREB1 (Ser133) 多克隆抗体
- 宿主：
Rabbit
- 适应物种：
Human;Mouse;Rat
- 目录编号：
E-AB-20849
- 级别：
科研级别
- 库存：
999
- 供应商：
武汉伊莱瑞特生物科技股份有限公司
- 标记物：
Unconjugated
- 克隆性：
Polyclonal
- 保存条件：
在-20℃下储存有效期为12个月。 避免冻融循环。
- 形态：
液体
- 亚型：
IgG
- 规格：
120μL/60μL/20μL
| 规格： | 120μL | 产品价格： | ￥2415.0 |
|---|---|---|---|
| 规格： | 60μL | 产品价格： | ￥1510.0 |
| 规格： | 20μL | 产品价格： | ￥630.0 |
Phospho-CREB1 (Ser133) 多克隆抗体产品名称：Phospho-CREB1 (Ser133) 多克隆抗体， 货号：E-AB-20849
| 已验证样本 | Western Blot（WB）已验证样本:MCF-7,A549,K562,HEK293 免疫组织化学（IHC）已验证样本:Human uterus 免疫荧光（IF）已验证样本:Mouse lung |
| 稀释 | WB 1:500-1:2000, IHC 1:100-1:300, IF 1:100-1:300, ELISA 1:5000-1:20000 |
| 克隆性 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | Synthesized peptide derived from human CREB-1 around the phosphorylation site of Ser133 |
| Abbre | CREB-1 (phospho Ser133) |
| 同义词 | Active transcription factor CREB;cAMP response element binding protein 1;cAMP response element binding protein;cAMP responsive element binding protein 1;cAMP-responsive element-binding protein 1;CREB;CREB-1;CREB1;CREB1;Cyclic AMP-responsive element-binding protein 1;MGC9284;OTTHUMP00000163864;OTTHUMP00000163865;OTTHUMP00000206660;OTTHUMP00000206662;OTTHUMP00000206667;Transactivator protein抗体 |
| Swissprot | P16220 |
| 计算的MW | 37kDa |
| 实测MW | 37kDa |
| 细胞定位 | Nucleus. |
| 浓度 | 1 mg/mL |
| 储存方法 | 在-20℃下储存有效期为12个月。 避免冻融循环。 |
| 缓冲 | PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4 |
| 纯化方法 | Affinity purification |
| 研究领域 | Cancer; Epigenetics and Nuclear Signaling; Immunology |
| Conjugation | Unconjugated |
| 产品描述： | This protein binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. CREB stimulates transcription on binding to the CRE. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Implicated in synchronization of circadian rhythmicity. |
Phospho-CREB1 (Ser133) 多克隆抗体Elabscience®流式抗体致力于为您的流式细胞分析实验带来更优质的体验，已有3,000+指标，选用经典克隆株纯化抗体，产品涵盖抗人/大鼠/小鼠等，指标丰富。
Phospho-CREB1 (Ser133) 多克隆抗体在-20℃下储存有效期为12个月。 避免冻融循环。
Phospho-CREB1 (Ser133) 多克隆抗体产品更多产品信息查看欢迎咨询我们和搜索武汉伊莱瑞特Elabscience官网查看。
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文献和实验Using Phospho‐Motif Antibodies to Determine Kinase Substrates
the phosphorylation site; therefore, substrate?directed, phosphorylation?state?sensitive, motif?specific (?phospho?motif?) antibodies represent powerful tools to identify novel kinase substrates and to investigate mechanisms of substrate phosphorylation
), and causes activation of KOR. Agonist-activated KOR becomes a substrate for G protein receptor kinase (GRK), which phosphorylates the Ser369 residue at the C-terminal tail of the receptor in the first step in the β-Arrestin-dependent desensitization cascade
at 10, 25, and 50 μM). At 24 h post-treatment, celllysates were obtained; SDS-PAGE and Western blotting were performed as described in Section 3, Methods. AR-A014418dose-dependent decreases of phospho-β-catenin (Ser33/37) and phospho-glycogen synthase
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