CD1A 单克隆抗体

免疫组织化学（IHC）已验证样本:Human tonsil
免疫荧光（IF）已验证样本:Mouse heart

IHC 1:100-1:300, IF 1:50-200

Monoclonal

IgG

Synthetic Peptide

CD1

CD 1a;CD1;CD1a;CD1A Antigen;CD1A antigen;a polypeptide;CD1a molecule;CD1A;cluster of differentiation 1 A;cortical thymocyte antigen CD1A;differentiation antigen CD1 alpha 3;epidermal dendritic cell marker CD1a;FCB 6;FCB6;HTA 1;HTA1;hTa1 thymocyte antigen;OTTHUMP00000018907;R 4;R4;T 6;T-cell surface antigen T6/Leu-6;T-cell surface glycoprotein CD1a;T6抗体

P06126

Cell membrane. Endosome membrane. Subject to intracellular trafficking between the cell membrane and endosomes. Localizes to cell surface lipid rafts.

Expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell leukemias, and in various other tissues.

1 mg/mL

在-20℃下储存有效期为12个月。 避免冻融循环。

PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Protein A purification

Cancer; Immunology

Clone:2A5

Unconjugated

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their 细胞定位 and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternatively spliced transcript variants have been observed, but their biological validity has not been determined.