人 PBX1 过表达慢病毒产品信息

人 PBX1 过表达慢病毒产品信息

订购信息

货号	种属	载体	描述	荧光	价格	周期
HZ002585	Human	腺病毒	Homo sapiens pre-B-cell leukemia homeobox 1 (PBX1), transcript variant 1, mRNA NM_002585	无荧光	8500 8000	6-7 周

基本信息

基因名称：	PBX1
NCBI序列号：	NM_002585
基因描述：	Homo sapiens pre-B-cell leukemia homeobox 1 (PBX1), transcript variant 1, mRNA NM_002585
基因种属：	Human
荧光标记：	无荧光
慢病毒滴度：	108 TU/ml

产品说明书

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基因简介

This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.