FBXW5抗体FBXW5兔多抗抗体F-box and WD-
40 domain-containing protein 5 antibody抗体FBXW5 Antibody, Biotin conjugated抗体- ￥880 - 1320
- CUSABIO
- CN
- CSB-PA846577LD01HU
- 2025年07月14日
- ELISA
- Rabbit
- Human
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- 文献和实验
- 技术资料
- 免疫原：
Recombinant Human F-box/WD repeat-containing protein 5 protein (265-494AA)
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性：
Polyclonal
- 标记物：
Biotin
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Homo sapiens (Human)
- 目录编号：
Q969U6
- 级别：
优
- 库存：
200
- 供应商：
武汉华美生物工程有限公司
- 宿主：
Rabbit
- 应用范围：
ELISA
- 浓度：
>95%,Protein G purified
- 靶点：
FBXW5
- 抗体英文名：
FBXW5 Antibody, Biotin conjugated
- 抗体名：
FBXW5 antibody;FBW5 antibody;PP3971F-box/WD repeat-containing protein 5 antibody;F-box and WD-40 domain-containing protein 5 antibody
- 规格：
100μg/50μg
| 规格： | 100μg | 产品价格： | ￥1320.0 |
|---|---|---|---|
| 规格： | 50μg | 产品价格： | ￥880.0 |
保存缓冲液
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
功能
Substrate recognition component of both SCF (SKP1-CUL1-F-box protein) and DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes. Substrate recognition component of the SCF(FBXW5) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SASS6 during S phase, leading to prevent centriole reduplication. The SCF(FBXW5) complex also mediates ubiquitination and degradation of actin-regulator EPS8 during G2 phase, leading to the transient degradation of EPS8 and subsequent cell shape changes required to allow mitotic progression. Substrate-specific adapter of the DCX(FBXW5) E3 ubiquitin-protein ligase complex which mediates the polyubiquitination and subsequent degradation of TSC2. May also act as a negative regulator of MAP3K7/TAK1 signaling in the interleukin-1B (IL1B) signaling pathway.风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Western Blotting with Monoclonal Ant
protein of cell or tissue lysate to each well of a 0.75mm thick gel. For thicker gels (1.5mm thick), apply up to 25-40µg in each well. 3.Electrophorese until the bromophenol blue in the samples reaches the bottom of the gel. Turn off power supply
Immunocytology using the HA epitope
to sit for 5 minutes before aspiration. This wash is repeated with PBS/0.1% BSA containing 0.1% NP40, then again with PBS/0.1% BSA. The cells are covered with PBS/0.1% BSA containing the secondary antibody (Table 1). The slide is set on wet paper
Purification of mAb (IgG) by Chang-Duk Jun, 03/14/2000 Purpose Materials Antibody 7E3 , 2L sup grown in flasks, frozen and thawed overnight. BioRad Affi-Gel Protein A MAPS II Buffers
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