- ￥2262
- LSM Bio
- 进口
- PAab03056
- 2025年07月10日
- ELISA,IHC,WB
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
F-box and WD repeat domain containing 5
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
Q9WVH4
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,IHC,WB
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
FBXW5
- 抗体英文名：
anti-FBXW5 antibody,FBXW5 antibody
- 抗体名：
anti-FBXW5 抗体,FBXW5 抗体
- 规格：
100μl
FBXW5抗体| FBXW5 antibody
货号 PAab03056
蛋白别名 FBW5
蛋白介绍
Substrate recognition component of both SCF (SKP1-CUL1- F-box protein) and DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes. Substrate recognition component of the SCF(FBXW5) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SASS6 during S phase, leading to prevent centriole reduplication. The SCF(FBXW5) complex also mediates ubiquitination and degradation of actin-regulator EPS8 during G2 phase, leading to the transient degradation of EPS8 and subsequent cell shape changes required to allow mitotic progression. Substrate-specific adapter of the DCX(FBXW5) E3 ubiquitin-protein ligase complex which mediates the polyubiquitination and subsequent degradation of TSC2. May also act as a negative regulator of MAP3K7/TAK1 signaling in the interleukin-1B (IL1B) signaling pathway.
产品描述
anti-FBXW5 antibody is a Rabbit Polyclonal antibody againstFBXW5..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human kidney tissue slide using PAab03056( FBXW5 Antibody) at dilution of 1:50
Western blot
HEK-293 cells were subjected to SDS PAGE followed by western blot with PAab03056( FBXW5 Antibody) at dilution of 1:600(本抗体仅供体外科研用途，不可用于临床诊断!)
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文献和实验
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