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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Synthesized non-phosphopeptide derived from Human IKK-γ around the phosphorylation site of serine 85 (Q-A-S(p)-Q-R).
- 亚型:
/
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
Polyclonal
- 标记物:
/
- 适应物种:
Human,Mouse
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
Q9Y6K9
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
ELISA,WB,IF;WB:1:500-1:3000,IF:1:100-1:500
- 浓度:
>95%,The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 靶点:
IKBKG
- 抗体英文名:
IKBKG (Ab-85) Antibody
- 抗体名:
/
- 规格:
100μl
保存缓冲液
/功能
Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However, the specific type of polyubiquitin recognized upon cell stimulation (either 'Lys-63'-linked or linear polyubiquitin) and its functional importance is reported conflictingly. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity. Essential for viral activation of IRF3. Involved in TLR3- and IFIH1-mediated antiviral innate response; this function requires 'Lys-27'-linked polyubiquitination.Li Y., Proc. Natl. Acad. Sci. U.S.A. 96:1042-1047(1999).
Jin D.-Y., J. Biomed. Sci. 6:115-120(1999).
Rothwarf D.M., Nature 395:297-300(1998).
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文献和实验dongreyuan 有的抗体名称上面写着Ab-33,比如,β-catenin(Ab-33)antibody,请问,Ab-33是什么意思? bettyzyj 这个抗体是非磷酸化的抗体non-phospho-antibody ,33 代表的是基因位点 dongreyuan 谢谢了 yhwangcams bettyzyj wrote
memoday 最近在做一个信号通路的下游磷酸化水平检测,但是做western没有看到任何条带,包括p-ERK,p85。麻烦各位战友帮我分析一下可能原因吧: 1.293T细胞转染质粒(带外源基因),24h 2.无血清培养18h 3.配体(外源基因是该配体的膜受体)激活,37度,10min 4.PLB(promega公司)裂解细胞,做western,抗体是SANTA CRUZ公司的p-ERK (Tyr 204),以及cell
CD85g/CD85h/CD85i/CD85j/CD85k/CD85l/CD85m分子
CD85g/CD85h/CD85i/CD85j/CD85k/CD85l/CD85m 分子 CD85g 常用单克隆抗体或代号:ILT7 CD85h 常用单克隆抗体或代号:ILT1/LIR7 CD85i 常用单克隆抗体或代号:LIR6 CD85j 常用单克隆抗体或代号:ILT2/LIRl,MIR7 主要表达细胞:NK.M,K,,B,T, 分子质量(kDa)和结构
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